Ali Kazemian, Borna Farazmand, Maryam Taherioun, Mahdie Razmkhah, Mohammad Shirkhoda, Amirmohsen Jalaeefar, Ata Garajei, Mehrdad Jafari, Farrokh Heidari, Mahdi Aghili, Reza Ghalehtaki
{"title":"The role of histology on the outcome of sinonasal carcinomas treated with radiotherapy: a single institution experience.","authors":"Ali Kazemian, Borna Farazmand, Maryam Taherioun, Mahdie Razmkhah, Mohammad Shirkhoda, Amirmohsen Jalaeefar, Ata Garajei, Mehrdad Jafari, Farrokh Heidari, Mahdi Aghili, Reza Ghalehtaki","doi":"10.3857/roj.2022.00514","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Sinonasal malignancies are a rare group of head and neck cancers. We aimed to report the oncological outcomes based on histological types in patients who underwent radiotherapy.</p><p><strong>Materials and methods: </strong>In this single-institution study, we retrospectively retrieved and analyzed data of patients with sinonasal carcinomas who underwent radiotherapy during 2011-2016 as part of their treatment. The 3-year rate of local, regional, and distant recurrences, and overall survival were evaluated according to the histological type.</p><p><strong>Results: </strong>A total of 28 patients were evaluated in this study, the majority of whom were male (60%). Squamous cell carcinoma (SCC), adenoid cystic carcinoma (ACC), and adenocarcinoma (ADC) were found in 15 patients (53.5%), 8 (28.5%), and 5 (18%), respectively. The highest rates of local and regional recurrences were observed in ACC and SCC, respectively. Distant recurrences were numerically more common in ADC. The 3-year OS was 48%, 50%, and 73% in SCC, ADC, and ACC, respectively.</p><p><strong>Conclusion: </strong>Different histopathologies of sinonasal cancer seem to have different patterns of failure, and this may be considered in the treatment approach.</p>","PeriodicalId":94184,"journal":{"name":"Radiation oncology journal","volume":"42 2","pages":"116-123"},"PeriodicalIF":0.0000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11215502/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiation oncology journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3857/roj.2022.00514","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/5/30 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: Sinonasal malignancies are a rare group of head and neck cancers. We aimed to report the oncological outcomes based on histological types in patients who underwent radiotherapy.
Materials and methods: In this single-institution study, we retrospectively retrieved and analyzed data of patients with sinonasal carcinomas who underwent radiotherapy during 2011-2016 as part of their treatment. The 3-year rate of local, regional, and distant recurrences, and overall survival were evaluated according to the histological type.
Results: A total of 28 patients were evaluated in this study, the majority of whom were male (60%). Squamous cell carcinoma (SCC), adenoid cystic carcinoma (ACC), and adenocarcinoma (ADC) were found in 15 patients (53.5%), 8 (28.5%), and 5 (18%), respectively. The highest rates of local and regional recurrences were observed in ACC and SCC, respectively. Distant recurrences were numerically more common in ADC. The 3-year OS was 48%, 50%, and 73% in SCC, ADC, and ACC, respectively.
Conclusion: Different histopathologies of sinonasal cancer seem to have different patterns of failure, and this may be considered in the treatment approach.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
