Helicobacter Pylori Prevalence in Communities from Southern Regions of Romania with Limited Access to Health Services: A Cross-sectional Study.

Radu Florin Prodan, Cristian Adrian Pintilie, Florina Iulia Ionete, Mihai Ciocirlan
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Abstract

Background and aims: Helicobacter pylori (H. pylori) infection has an unknown prevalence in certain Romanian regions. We aimed to estimate it in communities from Southern regions of Romania with limited access to health services.

Methods: We designed a cross-sectional study to include adult voluntary participants in the "Health in the neighborhood" medical assistance program. This was offered in villages with deprived healthcare availability from Southern regions of Romania. An immunochromatographic assay for the qualitative detection of H. pylori stool antigen was used for testing.

Results: We included 708 adult voluntary participants in 10 villages, 6 from Muntenia and Oltenia Regions (Southern Romania), 2 from Dobrogea and 2 from Moldova (2.4% of all village inhabitants). H. pylori prevalence in Romanian Southern regions was 28.2%, (95%CI: 24-32.6%), and overall was 27.1%, (95%CI: 23.9-30.6%). There were no significant differences of H. pylori infection pertaining to regions distribution (p=0.711), gender ratio (p=0.779), age distribution (p=0.471) and hemoglobin value (p=0.503).

Conclusions: H. pylori prevalence in communities from Southern regions of Romania with limited access to health services was 28.2%, 95%CI: 24-32.6%.

罗马尼亚南部地区社区幽门螺杆菌流行率(医疗服务有限):横断面研究。
背景和目的:幽门螺杆菌(H. pylori)感染在罗马尼亚某些地区的发病率不详。我们旨在对罗马尼亚南部地区医疗服务有限的社区的幽门螺杆菌感染率进行估计:我们设计了一项横断面研究,研究对象包括自愿参加 "邻里健康 "医疗援助计划的成年人。该计划在罗马尼亚南部地区医疗服务匮乏的村庄开展。我们采用免疫层析法对幽门螺杆菌粪便抗原进行定性检测:我们纳入了 10 个村庄的 708 名成年自愿参与者,其中 6 人来自 Muntenia 和 Oltenia 地区(罗马尼亚南部),2 人来自 Dobrogea,2 人来自摩尔多瓦(占所有村庄居民的 2.4%)。罗马尼亚南部地区的幽门螺杆菌感染率为 28.2%(95%CI:24-32.6%),总体感染率为 27.1%(95%CI:23.9-30.6%)。幽门螺杆菌感染与地区分布(P=0.711)、性别比例(P=0.779)、年龄分布(P=0.471)和血红蛋白值(P=0.503)无明显差异:罗马尼亚南部地区社区幽门螺杆菌感染率为 28.2%,95%CI:24-32.6%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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