Clinical outcomes of femtosecond laser-assisted corneal allogenic intrastromal ring segment (CAIRS) in the treatment of keratoconus

IF 4.9 2区医学 Q1 OPHTHALMOLOGY

Clinical and Experimental Ophthalmology Pub Date : 2024-06-27 DOI:10.1111/ceo.14411

Ahmet Kirgiz MD, Burcu Kemer Atik MD, Merve Emul MD, Muhittin Taskapili MD

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Abstract

Background

To evaluate the results of corneal allogenic intrastromal ring segment (CAIRS) implantation in keratoconus.

Methods

The medical records of patients with keratoconus who underwent CAIRS implantation were reviewed. The CAIRS, prepared by trephination from the donor cornea, was implanted into a tunnel created using the femtosecond laser. The depth of the tunnel was 200 μ; the inner diameter of the tunnel was 4.5 mm; and the outer diameter was 7 mm. Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), keratometry, minimum corneal thickness (CT), endothelial cell density (ECD), and high order aberration values were recorded preoperatively and at the 1st, 3rd, and 6th months postoperatively.

Results

A total of 23 eyes of 23 patients were included in the study. Preoperative UCVA (0.08 ± 0.01) and BCVA (0.25 ± 0. 11) values improved postoperatively and reached 0.40 ± 0.05 and 0.68 ± 0.09, respectively, at the end of the 6-month follow-up period (p¹ < 0.001, p² = 0.016; respectively). A statistically significant flattening of all keratometric values was observed in the postoperative period compared to preoperatively (p < 0.001 for all). There were no statistical differences between CT and ECC values at the preoperative and postoperative visits (p¹ = 0.654, p² = 0.769; respectively). In addition, coma aberration values were lower than the preoperative values at all postoperative visits (p < 0.05 for all).

Conclusions

These results suggest that CAIRS implantation is a safe treatment option with good visual and keratometric outcomes for suitable patients with keratoconus.

Abstract Image

查看原文本刊更多论文

飞秒激光辅助角膜同种异体基质内环段（CAIRS）治疗角膜炎的临床效果。

背景：评估异体角膜基质内环段（CAIRS）植入角膜的效果：评估角膜同种异体基质内环节段（CAIRS）植入术在角膜屈光不正中的效果：方法：回顾了接受 CAIRS 植入术的角膜炎患者的病历。CAIRS由供体角膜切削制备而成，被植入用飞秒激光创建的隧道中。隧道深度为 200 μ，内径为 4.5 mm，外径为 7 mm。记录术前、术后第 1、3 和 6 个月的未矫正视力 (UCVA)、最佳矫正视力 (BCVA)、角膜度数、最小角膜厚度 (CT)、内皮细胞密度 (ECD) 和高阶像差值：研究共纳入了 23 名患者的 23 只眼睛。术前的 UCVA（0.08 ± 0.01）和 BCVA（0.25 ± 0.11）值在术后均有所改善，在 6 个月的随访期结束时分别达到 0.40 ± 0.05 和 0.68 ± 0.09（p1 2 = 0.016；分别为 0.40 ± 0.05 和 0.68 ± 0.09）。与术前相比，术后所有角膜测量值都出现了统计学意义上的明显变平（p1 = 0.654，p2 = 0.769；分别为0.654和0.769）。此外，在所有术后检查中，昏迷像差值均低于术前值（p 结论：术后所有检查均显示昏迷像差值低于术前值：这些结果表明，对于合适的角膜病患者来说，CAIRS 植入术是一种安全的治疗方案，具有良好的视觉和角膜测量效果。

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来源期刊

Clinical and Experimental Ophthalmology 医学-眼科学

CiteScore

7.60

自引率

12.50%

发文量

150

审稿时长

4-8 weeks

期刊介绍： Clinical & Experimental Ophthalmology is the official journal of The Royal Australian and New Zealand College of Ophthalmologists. The journal publishes peer-reviewed original research and reviews dealing with all aspects of clinical practice and research which are international in scope and application. CEO recognises the importance of collaborative research and welcomes papers that have a direct influence on ophthalmic practice but are not unique to ophthalmology.