Transient Receptor Potential (TRP) Channels in Cochlear Function: Looking Beyond Mechanotransduction.

IF 2.4 3区医学 Q3 NEUROSCIENCES

Jaro-Journal of the Association for Research in Otolaryngology Pub Date : 2024-10-01 Epub Date: 2024-06-26 DOI:10.1007/s10162-024-00954-1

Trinh Nguyen, Dwight E Bergles

引用次数: 0

Abstract

Transient receptor potential (TRP) channels play key roles in sensory biology as transducers of various stimuli. Although these ion channels are expressed in the cochlea, their functions remain poorly understood. Recent studies by Vélez-Ortega and colleagues indicate that their expression by non-sensory supporting cells helps limit damage from acoustic trauma.

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耳蜗功能中的瞬态受体电位（TRP）通道：超越机械传导。

瞬时受体电位（TRP）通道在感官生物学中扮演着重要角色，是各种刺激的传导者。虽然这些离子通道在耳蜗中也有表达，但人们对它们的功能仍然知之甚少。Vélez-Ortega 及其同事最近的研究表明，非感觉支持细胞表达这些通道有助于限制声创伤造成的损害。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Jaro-Journal of the Association for Research in Otolaryngology 医学-耳鼻喉科学

CiteScore

4.10

自引率

12.50%

发文量

审稿时长

6-12 weeks

期刊介绍： JARO is a peer-reviewed journal that publishes research findings from disciplines related to otolaryngology and communications sciences, including hearing, balance, speech and voice. JARO welcomes submissions describing experimental research that investigates the mechanisms underlying problems of basic and/or clinical significance. Authors are encouraged to familiarize themselves with the kinds of papers carried by JARO by looking at past issues. Clinical case studies and pharmaceutical screens are not likely to be considered unless they reveal underlying mechanisms. Methods papers are not encouraged unless they include significant new findings as well. Reviews will be published at the discretion of the editorial board; consult the editor-in-chief before submitting.