A severe pediatric life-threatening metabolic ketoacidosis.

IF 1.8 Q4 ENDOCRINOLOGY & METABOLISM
Journal of Diabetes and Metabolic Disorders Pub Date : 2024-03-25 eCollection Date: 2024-06-01 DOI:10.1007/s40200-024-01410-w
Charlotte Roulland, Catline Le Pallec, Caroline Faucon, Camille O Andre, Alina Arion, Isabelle Goyer, David Brossier
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引用次数: 0

Abstract

This case report presents a 9-year-old child without underlying pathology, with a severe life-threatening non-diabetic metabolic ketoacidosis occurring less than 48 h after the onset of fasting and vomiting. The patient was admitted to the pediatric intensive care unit. He received volume expansion and maintenance fluid therapy which allowed a favorable evolution. Because of the unusual rapid onset of intense ketonemia and acidosis, a hereditary metabolic disease was investigated. The association between short fasting period and severe metabolic ketoacidosis has never been described in children outside of the neonatal period. This clinical case emphasizes urgent recognition, rigorous diagnostic and appropriate management in clinical practice.

危及生命的严重儿科代谢性酮症酸中毒。
本病例报告介绍了一名 9 岁儿童在没有潜在病症的情况下,在开始禁食和呕吐不到 48 小时后发生严重的非糖尿病代谢性酮症酸中毒,危及生命。患者被送入儿科重症监护室。他接受了容量扩充和维持性输液治疗,病情发展顺利。由于强烈酮血症和酸中毒的发病速度异常之快,研究人员对遗传性代谢疾病进行了调查。在新生儿期以外的儿童中,从未出现过禁食时间短与严重代谢性酮症酸中毒之间的关联。该临床病例强调了临床实践中的紧急识别、严格诊断和适当处理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Diabetes and Metabolic Disorders
Journal of Diabetes and Metabolic Disorders Medicine-Internal Medicine
CiteScore
4.80
自引率
3.60%
发文量
210
期刊介绍: Journal of Diabetes & Metabolic Disorders is a peer reviewed journal which publishes original clinical and translational articles and reviews in the field of endocrinology and provides a forum of debate of the highest quality on these issues. Topics of interest include, but are not limited to, diabetes, lipid disorders, metabolic disorders, osteoporosis, interdisciplinary practices in endocrinology, cardiovascular and metabolic risk, aging research, obesity, traditional medicine, pychosomatic research, behavioral medicine, ethics and evidence-based practices.As of Jan 2018 the journal is published by Springer as a hybrid journal with no article processing charges. All articles published before 2018 are available free of charge on springerlink.Unofficial 2017 2-year Impact Factor: 1.816.
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