Prostate Metastasis in Oral Malignant Melanoma - A Case Report.

Q3 Dentistry
Indian Journal of Dental Research Pub Date : 2024-01-01 Epub Date: 2024-06-20 DOI:10.4103/ijdr.ijdr_376_23
Vaishnavi Muthukumaran, S Aravind Warrier, Barath Balaji, S Elengkumaran, H Thamizhchelvan, C V Divyambika
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引用次数: 0

Abstract

Abstract: Melanoma is the ninth most prevalent and the second most lethal tumour. The aetiology and pathogenesis remain uncertain. It occurs in elderly people, over the fifth decade, and is predominant in males. Clinically, they present as an asymptomatic macular or nodular growth. The prognosis is impacted by the size of the tumour and distant metastases. Patients with distant metastases have a 5-year survival rate of less than 30%, constituting metastasis as the major cause of melanoma-related fatality. Currently, the mainstay of treatment for metastatic melanoma is immunotherapy due to the inoperable state, radioresistant nature of the tumour and high chances of cytotoxicity in chemotherapy. A senile male patient, who was diagnosed with oral malignant melanoma of the maxillary buccopalatal gingiva with distant metastasis to the liver and the prostate, is reported here. Although metastasis to the liver is common among malignant melanomas, in this case metastasis to the prostate gland highlights the rarity.

口腔恶性黑色素瘤的前列腺转移--病例报告。
摘要:黑色素瘤是发病率第九高、致死率第二高的肿瘤。其病因和发病机制尚不明确。它好发于五六十岁以上的老年人,男性居多。临床表现为无症状的黄斑或结节状生长。预后受肿瘤大小和远处转移的影响。有远处转移的患者 5 年生存率不到 30%,因此转移是黑色素瘤致死的主要原因。目前,转移性黑色素瘤的主要治疗手段是免疫疗法,因为这种肿瘤无法手术,对放射线具有抗药性,而且化疗中细胞毒性的几率很高。本文报告了一名老年男性患者,他被诊断为上颌颊腭龈口腔恶性黑色素瘤,并远处转移至肝脏和前列腺。虽然转移到肝脏在恶性黑色素瘤中很常见,但在该病例中,转移到前列腺的情况更加罕见。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Indian Journal of Dental Research
Indian Journal of Dental Research Dentistry-Dentistry (all)
CiteScore
1.80
自引率
0.00%
发文量
80
审稿时长
38 weeks
期刊介绍: Indian Journal of Dental Research (IJDR) is the official publication of the Indian Society for Dental Research (ISDR), India section of the International Association for Dental Research (IADR), published quarterly. IJDR publishes scientific papers on well designed and controlled original research involving orodental sciences. Papers may also include reports on unusual and interesting case presentations and invited review papers on significant topics.
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