Pediatric-type diffuse low-grade gliomas.

IF 1.3 4区医学 Q4 CLINICAL NEUROLOGY

Child's Nervous System Pub Date : 2024-10-01 Epub Date: 2024-06-26 DOI:10.1007/s00381-024-06500-x

Asthik Biswas, Harini R Rao, Matthias W Wagner

引用次数: 0

Abstract

The World Health Organization's 5th edition classification of Central Nervous System (CNS) tumors differentiates diffuse gliomas into adult and pediatric variants. Pediatric-type diffuse low-grade gliomas (pDLGGs) are distinct from adult gliomas in their molecular characteristics, biological behavior, clinical progression, and prognosis. Various molecular alterations identified in pDLGGs are crucial for treatment. There are four distinct entities of pDLGGs. All four of these tumor subtypes exhibit diffuse growth and share overlapping histopathological and imaging characteristics. Molecular analysis is essential for differentiating these lesions.

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小儿型弥漫性低级别胶质瘤。

世界卫生组织第五版中枢神经系统（CNS）肿瘤分类将弥漫性胶质瘤分为成人型和儿童型。儿童型弥漫性低级别胶质瘤（pDLGGs）在分子特征、生物学行为、临床进展和预后方面均有别于成人胶质瘤。在 pDLGGs 中发现的各种分子改变对治疗至关重要。pDLGGs有四种不同的实体。这四种肿瘤亚型均表现为弥漫性生长，并具有重叠的组织病理学和影像学特征。分子分析对于区分这些病变至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Child's Nervous System 医学-临床神经学

CiteScore

3.00

自引率

7.10%

发文量

322

审稿时长

3 months

期刊介绍： The journal has been expanded to encompass all aspects of pediatric neurosciences concerning the developmental and acquired abnormalities of the nervous system and its coverings, functional disorders, epilepsy, spasticity, basic and clinical neuro-oncology, rehabilitation and trauma. Global pediatric neurosurgery is an additional field of interest that will be considered for publication in the journal.