Outbreak of Burkholderia cenocepacia in an intensive care unit of a tertiary care hospital identified by pulsed-field gel electrophoresis

IF 1.4 4区医学 Q4 IMMUNOLOGY

Indian Journal of Medical Microbiology Pub Date : 2024-07-01 DOI:10.1016/j.ijmmb.2024.100655

Mahalakshmi Kumaresan, Meerabai Manoharan, Madhan Sugumar, Sujatha Sistla

引用次数: 0

Abstract

Nosocomial outbreaks of Burkholderia cepacia complex, transmitted through contaminated medical surfaces or equipment have been reported. Pulsed-field Gel Electrophoresis (PFGE) is recognized as the “gold standard” for molecular subtyping, yet studies on clonal relationships in India are limited. PFGE was used to study the clonal relationships of 22 isolates of Burkholderia cenocepacia from 12 patients admitted to a critical care unit during 2 months (November and December 2021). PFGE revealed three different profiles with 15 isolates belonging to a single cluster suggesting a common source within the hospital, emphasizing the need for preventive measures to control B. cenocepacia transmission.

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通过脉冲场凝胶电泳鉴定一家三甲医院重症监护室爆发的伯克霍尔德氏伤寒杆菌。

有报告称，通过受污染的医疗表面或设备传播的伯克霍尔德氏菌复合体在医院内爆发。脉冲场凝胶电泳（PFGE）被认为是分子亚型鉴定的 "黄金标准"，但在印度对克隆关系的研究却很有限。在两个月（2021 年 11 月和 12 月）的时间里，我们利用脉冲场凝胶电泳技术研究了从重症监护室收治的 12 名患者中分离出的 22 株伯克霍尔德氏菌的克隆关系。PFGE 显示了三种不同的图谱，其中 15 个分离株属于一个群集，这表明医院内存在一个共同的来源，强调了采取预防措施控制伯克霍尔德氏菌传播的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Medical Microbiology IMMUNOLOGY-

CiteScore

2.20

自引率

0.00%

发文量

154

审稿时长

73 days

期刊介绍： Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.