Early Outcomes of Hirschsprung's Disease after Definitive Surgery: A Ten-Year Experience.

IF 1.3 Q3 PEDIATRICS

Current Pediatric Reviews Pub Date : 2024-06-20 DOI:10.2174/0115733963271997240605103909

Muntadhar Muhammad Isa, Maimun Syukri, Muchlisin Za, Gunadi, Dian Adi Syahputra, T Yusriadi, Yumna Muzakkir, Siti Maghfirah

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Abstract

Introduction: This study aimed to examine the characteristics of Hirschsprung's Disease (HD) in patients aged<18 who underwent surgical procedure at Dr. Zainoel Abidin (RSUDZA) General Hospital, Banda Aceh, Indonesia, between January 2010 and December 2020.

Methods: This retrospective study collected and analyzed data from medical records of 18-yearold or younger children (n = 180) diagnosed with HD at RSUDZA. The surgical procedures included the Duhamel procedure, Soave procedure, the Soave Transanal Endorectal Pull-through (TEPT) procedure, and the Swenson TEPT procedure. Early outcomes of the surgery were then compared between males and females. The comparrative analysis was determined based on Chisquare analysis, where p< 0.05 was considered significant.

Results: There were 111 (61.7%) male patients and 69 (38.3%) female patients, with a mean age of 15.2 months. The Soave TEPT is the most frequently performed procedure (91.7%). Emerging clinical manifestations include constipation (176; 97.8%) and soiling (171; 95%). Preoperative barium enema and postoperative pathological examination confirmed that almost all patients (99.4%) had an aganglionic segment confined to the rectosigmoid area. The average length of operation was 69.7 ± 65 minutes and average bleeding time was 5.4 ± 34 mL. The average discharge time was 3.3 ± 73.3 days. No significant difference was found in post-surgery complications between males and females (p<0.5). The immediate complications were not associated with surgical methods (p = 0.83).

Conclusion: Our descriptive study has suggested the Soave TEPT technique as appropriate to manage HD.

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确定性手术后的赫氏胃肠病早期疗效：十年经验

导言：本研究旨在探讨年龄在 18 岁以下的赫氏胃肠病（Hirschsprung's Disease，HD）患者的特征：这项回顾性研究收集并分析了在皇家研究与发展中心（RSUDZA）确诊的18岁或18岁以下HD患儿（180人）的病历数据。手术方法包括 Duhamel 手术、Soave 手术、Soave 经肛门直肠内拉穿（TEPT）手术和 Swenson TEPT 手术。然后对男性和女性的早期手术结果进行比较。比较分析基于Chisquare分析，P< 0.05为显著：男性患者 111 人（61.7%），女性患者 69 人（38.3%），平均年龄 15.2 个月。Soave TEPT 是最常用的手术（91.7%）。新出现的临床表现包括便秘（176 例；97.8%）和便溺（171 例；95%）。术前钡剂灌肠和术后病理检查证实，几乎所有患者（99.4%）的aganglionic节段都局限于直肠乙状结肠区域。手术平均时间为 69.7 ± 65 分钟，平均出血时间为 5.4 ± 34 毫升。平均出院时间为 3.3 ± 73.3 天。男性和女性的术后并发症无明显差异（p<0.5）。即时并发症与手术方法无关（p = 0.83）：我们的描述性研究表明，Soave TEPT 技术适用于治疗 HD。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Pediatric Reviews PEDIATRICS-

CiteScore

4.30

自引率

0.00%

发文量

期刊介绍： Current Pediatric Reviews publishes frontier reviews on all the latest advances in pediatric medicine. The journal’s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in pediatric medicine.

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