Prevalence of cognitive frailty and its associated factors in a population of Iranian older adults.

IF 3.4 3区 医学 Q2 GERIATRICS & GERONTOLOGY
Mohammad Javad Ghanbarnia, Seyed Reza Hosseini, Alijan Ahmadi Ahangar, Reza Ghadimi, Ali Bijani
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Abstract

Background: In recent years cognitive frailty has emerged as an important predictor of adverse health outcomes in older adults. Herein, we aimed to investigate the prevalence and associated factors of cognitive frailty in a population of community-dwelling older adults in Iran.

Method: This cross-sectional study was conducted as part of the second cycle of the Amirkola Health and Aging Project (AHAP). Physical frailty and cognitive impairment were evaluated using the FRAIL questionnaire and the mini-mental state examination (MMSE) respectively. Cognitive frailty was defined as co-existence of frailty and cognitive impairment without presence of dementia. Depression and disability were assessed using the Persian version of geriatric depression scale (GDS) and instrumental activities of daily living (IADL) questionnaire.

Results: Overall 1775 individuals (47.1% female) with mean age of 69.7 ± 7.3 years were included in the final analysis. The prevalence of cognitive frailty was 12.0%. The prevalence of cognitive frailty among males and females was 4.3% and 20.7%, respectively. After adjusting for all possible confounders through binary logistic regression analysis, factors such as older age (OR 1.06, CI 1.03-1.09), female gender (OR 2.25, CI 1.42-3.57), illiteracy (OR 3.84, CI 2.03-8.29), more comorbidities (OR 1.21, CI 1.12-1.31), depression (OR 2.01, CI 1.40-2.86), and greater IADL disability (OR 1.68, CI 1.44-3.96), were independently and significantly associated with cognitive frailty.

Conclusion: In this population of Iranian older adults, prevalence of cognitive frailty was consistent with its estimated mean global prevalence. Age, gender, illiteracy, comorbidities, depression and IADL disability were associated with cognitive frailty. Further research is required to develop screening tools and prevention strategies.

Abstract Image

伊朗老年人认知能力衰弱及其相关因素。
背景:近年来,认知虚弱已成为预测老年人不良健康后果的一个重要因素。在此,我们旨在调查伊朗社区老年人群中认知虚弱的流行率和相关因素:这项横断面研究是阿米尔科拉健康与老龄化项目(AHAP)第二周期的一部分。身体虚弱和认知障碍分别通过 FRAIL 问卷和小型精神状态检查 (MMSE) 进行评估。认知功能虚弱被定义为同时存在虚弱和认知功能障碍,但不伴有痴呆症。抑郁和残疾情况使用波斯语版老年抑郁量表(GDS)和日常生活工具活动(IADL)问卷进行评估:最终分析共纳入 1775 名患者(47.1% 为女性),平均年龄为 69.7 ± 7.3 岁。认知功能衰弱的发生率为 12.0%。男性和女性的认知虚弱发生率分别为 4.3% 和 20.7%。29)、更多的合并症(OR 1.21,CI 1.12-1.31)、抑郁(OR 2.01,CI 1.40-2.86)和更大的 IADL 残疾(OR 1.68,CI 1.44-3.96)与认知虚弱独立且显著相关:在伊朗老年人群中,认知功能衰弱的发生率与其估计的全球平均发生率一致。年龄、性别、文盲、合并症、抑郁症和 IADL 残疾与认知虚弱有关。需要进一步开展研究,以制定筛查工具和预防策略。
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来源期刊
CiteScore
7.90
自引率
5.00%
发文量
283
审稿时长
1 months
期刊介绍: Aging clinical and experimental research offers a multidisciplinary forum on the progressing field of gerontology and geriatrics. The areas covered by the journal include: biogerontology, neurosciences, epidemiology, clinical gerontology and geriatric assessment, social, economical and behavioral gerontology. “Aging clinical and experimental research” appears bimonthly and publishes review articles, original papers and case reports.
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