Epidemiological and clinicopathological characteristics of colorectal cancer patients in tertiary hospital in West Java

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2024-06-18 DOI:10.1016/j.cegh.2024.101688

Kiki Lukman , Arrayyan Muhammad , Mohammad Ghozali , Prapanca Nugraha , Yunia Sribudiani , Bistamy Muhammad Nursabur

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引用次数: 0

Abstract

Problem considered

Colorectal cancer (CRC) is the third most frequently diagnosed type of cancer in Indonesia, accounting for around 8.5% of cancer cases. This study aims to know the epidemiological and clinicopathological characteristics of CRC patients in Tertiary Hospital in West Java.

Methods

This study was a cross-sectional study. All the data were obtained from Hasan Sadikin General Hospital CRC Registry from November 2021 until May 2023.

Results

208 colorectal cancer patients were analyzed. The average age at diagnosis was 52,9 (52 ± 13.1) with 61% diagnosed over 50. More females (51%) were diagnosed. Smoking history included 37.5% active smokers and 41.8% passive exposure. Nutritionally, 65.8% were normal weight, 30.7% underweight, and 5% overweight. The most common presenting symptoms were constipation (49%) and rectal bleeding (38%). Stage III and IV were diagnosed in 77% of patients. Left-sided colon tumors (85%) were most frequent, with adenocarcinoma not otherwise specified (98%) being the dominant histology. Bowel obstruction (68%) was the most common complication.

Conclusion

CRC in Hasan Sadikin General Hospital was frequently diagnosed at a late stage, with a relatively high percentage of patients were below 50 years. Left-sided CRC and histological types of adenocarcinoma not otherwise specified were still the most common pathological features of CRC. Future research is needed to discover the potential multifactorial causes of this phenomenon.

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西爪哇三级医院结直肠癌患者的流行病学和临床病理学特征

考虑的问题大肠癌（CRC）是印度尼西亚第三大最常见的癌症类型，约占癌症病例的 8.5%。本研究旨在了解西爪哇省三级医院中 CRC 患者的流行病学和临床病理学特征。所有数据均来自哈桑-萨迪金综合医院（Hasan Sadikin General Hospital）2021 年 11 月至 2023 年 5 月期间的 CRC 登记处。诊断时的平均年龄为 52.9 岁（52 ± 13.1），其中 61% 的诊断年龄超过 50 岁。女性患者较多（51%）。吸烟史包括 37.5% 的主动吸烟者和 41.8% 的被动吸烟者。营养状况方面，65.8%的患者体重正常，30.7%体重不足，5%超重。最常见的症状是便秘（49%）和直肠出血（38%）。77%的患者被诊断为 III 期和 IV 期。左侧结肠肿瘤（85%）最常见，主要组织学类型为未特殊说明的腺癌（98%）。肠梗阻（68%）是最常见的并发症。左侧 CRC 和未注明组织学类型的腺癌仍然是 CRC 最常见的病理特征。未来的研究需要发现造成这一现象的潜在多因素原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.