Patient-reported outcomes and experiences of migrants enrolled in a multidisciplinary HIV clinic with rapid, free, and onsite treatment dispensation: the 'ASAP' study.

IF 2.1 4区 医学 Q3 INFECTIOUS DISEASES
Anish K Arora, Serge Vicente, Kim Engler, David Lessard, Edmundo Huerta, Joel Ishak, Nadine Kronfli, Jean-Pierre Routy, Joseph Cox, Benoit Lemire, Marina Klein, Alexandra de Pokomandy, Lina Del Balso, Giada Sebastiani, Isabelle Vedel, Amélie Quesnel-Vallée, Bertrand Lebouché
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引用次数: 0

Abstract

Background: Scholars recommend providing migrants living with HIV (MLWH) with free treatment, rapidly, once linked to care to optimize their HIV-related experiences and health outcomes. Quantitative evaluations of patient-reported measures for MLWH in such models are necessary to explore the viability of these recommendations.

Methods: Within a 96-week prospective cohort study at a multidisciplinary HIV clinic, participants received bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) for free and rapidly following care linkage. Eight patient-reported measures were administered at weeks 4, 24, and 48: (1) mMOS-SS to measure perceived social support; (2) IA-RSS to measure internalized stigma; (3) K6 to measure psychological distress; (4) PROMIS to measure self-efficacy with treatment taking; (5) G-MISS to measure perceived compliance with clinicians' treatment plans; (6) HIVTSQ to measure treatment satisfaction; (7) CARE to measure perceived provider empathy; and (8) PRPCC to measure perceived clinician cultural competence. Linear mixed modelling with bootstrapping was conducted to identify significant differences by sociodemographics and time.

Results: Across weeks 4, 24, and 48, results suggest that MLWH enrolled in this study experienced moderate levels of social support; elevated levels of HIV-related stigma; moderate levels of distress; high self-efficacy with daily medication self-management; great compliance with clinicians' treatment plans; high treatment satisfaction; high perceived empathy; and high perceived cultural competence. Experience of social support (i.e., mMOS-SS scores) differed significantly by birth region. Experience of HIV-related stigma (i.e., IA-RSS scores) differed significantly by birth region, age, and language. Experience of distress (i.e., K6 scores) differed significantly by sexual orientation. Experience of treatment satisfaction (i.e., HIVTSQ scores) differed significantly by birth region and age. No significant differences were identified by time for any measure.

Conclusion: Overall, participants expressed positive experiences around treatment and care, alongside comparably lower perceptions of social support, internalized stigma, and distress, potentially underscoring a need to embed targeted, well-funded, and accessible mental health support within HIV care models.

患者报告的结果以及在多学科艾滋病诊所接受快速、免费和现场治疗的移民的经历:"ASAP "研究。
背景:学者们建议为感染艾滋病病毒的移民(MLWH)提供免费治疗,一旦与护理建立联系,就迅速提供免费治疗,以优化他们与艾滋病相关的经历和健康结果。为了探讨这些建议的可行性,有必要在此类模式中对患者报告的 MLWH 指标进行定量评估:方法:在一家多学科 HIV 诊所进行的一项为期 96 周的前瞻性队列研究中,参与者免费接受比特拉韦/恩曲他滨/替诺福韦-阿拉非那胺(B/F/TAF)治疗,并在治疗连接后迅速接受治疗。在第 4、24 和 48 周进行了八项患者报告测量:(1) mMOS-SS 用于测量感知的社会支持;(2) IA-RSS 用于测量内化的污名;(3) K6 用于测量心理困扰;(4) PROMIS 用于测量接受治疗的自我效能;(5) G-MISS 用于测量感知的对临床医生治疗计划的依从性;(6) HIVTSQ 用于测量治疗满意度;(7) CARE 用于测量感知的提供者同理心;(8) PRPCC 用于测量感知的临床医生文化能力。采用自举法进行线性混合建模,以确定社会人口统计学和时间的显著差异:在第 4 周、第 24 周和第 48 周,研究结果表明,参与本研究的产妇和新生儿获得了中等程度的社会支持;与 HIV 相关的污名化程度升高;中等程度的痛苦;日常药物自我管理的自我效能高;对临床医生治疗计划的依从性高;治疗满意度高;感知到的同理心高;感知到的文化能力高。出生地区不同,社会支持体验(即 mMOS-SS 分数)也有显著差异。不同出生地区、不同年龄和不同语言的受访者对艾滋病相关污名化的感受(即 IA-RSS 评分)差异显著。不同性取向人群的痛苦体验(即 K6 分数)差异显著。治疗满意度(即 HIVTSQ 分数)因出生地区和年龄而有显著差异。结论:总体而言,参与者对治疗的满意度较高:总体而言,参与者对治疗和护理有积极的体验,同时对社会支持、内化污名化和痛苦的感知相对较低,这可能强调了在艾滋病护理模式中嵌入有针对性的、资金充足的和可获得的心理健康支持的必要性。
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来源期刊
AIDS Research and Therapy
AIDS Research and Therapy INFECTIOUS DISEASES-
CiteScore
3.80
自引率
4.50%
发文量
51
审稿时长
16 weeks
期刊介绍: AIDS Research and Therapy publishes articles on basic science, translational, clinical, social, epidemiological, behavioral and educational sciences articles focused on the treatment and prevention of HIV/AIDS, and the search for the cure. The Journal publishes articles on novel and developing treatment strategies for AIDS as well as on the outcomes of established treatment strategies. Original research articles on animal models that form an essential part of the AIDS treatment research are also considered
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