A journey through the world of vitreous

IF 5.1 2区 医学 Q1 OPHTHALMOLOGY
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引用次数: 0

Abstract

Vitreous, one of the largest components of the human eye, mostly contains water. Despite decades of studying the vitreous structure, numerous unanswered questions still remain, fueling ongoing active research. We attempt to provide a comprehensive overview of the current understanding of the development, morphology, biochemical composition, and function of the vitreous. We emphasize the impact of the vitreous structure and composition on the distribution of drugs. Fast-developing imaging technologies, such as modern optical coherence tomography, unlocked multiple new approaches, offering the potential for in vivo study of the vitreous structure. They allowed to analyze in vivo a range of vitreous structures, such as posterior precortical vitreous pockets, Cloquet canal, channels that interconnect them, perivascular vitreous fissures, and cisterns. We provide an overview of such imaging techniques and their principles and of some challenges in visualizing vitreous structures. Finally, we explores the potential of combining the latest technologies and machine learning to enhance our understanding of vitreous structures.

玻璃体世界之旅
玻璃体是人眼最大的组成部分之一,主要含水。尽管对玻璃体结构进行了数十年的研究,但仍有许多未解之谜,这也推动了当前的积极研究。我们试图全面概述目前对玻璃体的发育、形态、生化成分和功能的理解。我们强调玻璃体结构和组成对药物分布的影响。快速发展的成像技术,如现代光学相干断层扫描,开启了多种新方法,为玻璃体结构的活体研究提供了可能。这些技术可以在体内分析一系列玻璃体结构,如后皮质前玻璃体袋、Cloquet 管、相互连接的通道、血管周围玻璃体裂隙和贮水池。我们概述了此类成像技术及其原理,以及玻璃体结构可视化所面临的一些挑战。最后,我们探讨了将最新技术与机器学习相结合以增强我们对玻璃体结构的理解的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Survey of ophthalmology
Survey of ophthalmology 医学-眼科学
CiteScore
10.30
自引率
2.00%
发文量
138
审稿时长
14.8 weeks
期刊介绍: Survey of Ophthalmology is a clinically oriented review journal designed to keep ophthalmologists up to date. Comprehensive major review articles, written by experts and stringently refereed, integrate the literature on subjects selected for their clinical importance. Survey also includes feature articles, section reviews, book reviews, and abstracts.
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