Factors influencing the level of insight and treatment attitude: a cross-sectional study of 141 elderly patients of major depression in Guangzhou, China

Hang Yang, Jiao Chen, Junrong Ye, Tingwei Zhou, Wen Wang, Yuanxin Pan, Yanheng Wei, Xueling Lu, Lexin Yuan, Shengwei Wu, Jianxiong Guo, Aixiang Xiao
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Abstract

To explore the insight, treatment attitude, and related influencing factors of hospitalized elderly patients suffering from major depression.A total of 141 hospitalized elderly patients with depression were selected as the research objects. Insight was evaluated by the total score of the Insight and Treatment Attitude questionnaire (ITAQ). The data collected included sociodemographic characteristics, psychiatric symptoms, delirium status, social functioning, social support, suicide risk, and cognitive function.The sample included 74.5% of female patients, and the mean age was 67.53 (sd=7.19) years. The influencing factors of inpatients with depression included alcohol consumption, length of hospitalization, admission types, and the main caregivers (P<0.05). The various factors were further analyzed by linear regression, revealing that the insight and treatment attitude of elderly depressed hospitalized patients were mainly related to the Mini-Mental State Examination (MMSE) (β= 0.225, 95% CI 0.055–0.395, P=0.01), dependent on a caregiver (β=-5.810, 95% CI -8.086~-3.535, P<0.001), the type of admission (involuntary admission) (β=-3.365, 95% CI -5.448~-1.283, P=0.002), Functional Activities Questionnaire (FAQ) (β=-0.156, 95% CI -0.303~-0.010, P=0.037), and length of stay (≤28 days) (β=2.272, 95% CI 0.055~-4.489, P=0.045).The level of insight was affected by cognitive function, involuntary admission, dependent on a caregiver, social function and length of stay. Future studies should focus on cognitive function recovery, observation of admission mode, and self-care ability in elderly patients with depression.
影响洞察力水平和治疗态度的因素:对中国广州 141 名老年重度抑郁症患者的横断面研究
目的:探讨住院老年重度抑郁症患者的洞察力、治疗态度及相关影响因素。洞察力通过洞察力和治疗态度问卷(ITAQ)的总分进行评估。收集的数据包括社会人口学特征、精神症状、谵妄状态、社会功能、社会支持、自杀风险和认知功能。住院抑郁症患者的影响因素包括饮酒量、住院时间、入院类型和主要照顾者(P<0.05)。对各种因素进一步进行线性回归分析,发现老年抑郁症住院患者的洞察力和治疗态度主要与小型精神状态检查(MMSE)(β= 0.225,95% CI 0.055-0.395,P=0.01)、依赖照护者(β=-5.810,95% CI -8.086~-3.535,P<0.001)、入院类型(非自愿入院)(β=-3.认知功能、非自愿入院、依赖照护者、社会功能和住院时间对洞察力水平有影响。未来的研究应关注老年抑郁症患者认知功能的恢复、入院方式的观察和自理能力。
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