Biogenic Amines and Their Role in the Brain

Abstract

The purpose of the review is to summarize and systematize the literature data on the metabolism, functions of biogenic amines in the brain, as well as their biochemical structure and classification. Biogenic amines play an important role in brain metabolism and its functioning. This is due to the exceptional role of biogenic amines as sources of synthesis of a large number of biologically important compounds, such as neuropeptides and hormones, and their participation in synaptic transmission as neurotransmitters and neuromodulators. Determination of the activity of enzyme systems of their metabolism can serve as an important diagnostic marker of the reaction of the central nervous system to damage in cerebral pathology.