Development and validation of an LC–MS/MS method for the determination of BLU-945, a fourth-generation EGFR tyrosine kinase inhibitor, in rat and mouse plasma: application to a pharmacokinetic study in rats

IF 2.5 4区化学 Q3 CHEMISTRY, ANALYTICAL

Journal of Analytical Science and Technology Pub Date : 2024-06-10 DOI:10.1186/s40543-024-00452-2

Ji‐Hoon Oh, Thi-Thao-Linh Nguyen, H. Maeng

引用次数: 0

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开发并验证用于测定大鼠和小鼠血浆中第四代表皮生长因子受体酪氨酸激酶抑制剂 BLU-945 的 LC-MS/MS 方法：在大鼠药代动力学研究中的应用

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来源期刊

Journal of Analytical Science and Technology Environmental Science-General Environmental Science

CiteScore

4.00

自引率

4.20%

发文量

审稿时长

13 weeks

期刊介绍： The Journal of Analytical Science and Technology (JAST) is a fully open access peer-reviewed scientific journal published under the brand SpringerOpen. JAST was launched by Korea Basic Science Institute in 2010. JAST publishes original research and review articles on all aspects of analytical principles, techniques, methods, procedures, and equipment. JAST’s vision is to be an internationally influential and widely read analytical science journal. Our mission is to inform and stimulate researchers to make significant professional achievements in science. We aim to provide scientists, researchers, and students worldwide with unlimited access to the latest advances of the analytical sciences.