Relationship between Troponin and Red Cell Distribution Width Levels and Mortality in Post-Covid Patients

Abstract

Introduction: There are very few studies on the TR value, which expresses the simultaneous increase in Troponin and Red Cell Distribution Width (RDW), which are markers of myocardial damage commonly seen in Covid-19 disease. This study aims to show the relationship of troponin, RDW and TR values with mortality and prognostic factors post-Covid-19. Methods: 204 patients diagnosed with Covid-19 who were admitted to the adult tertiary Covid ICU between April,2021 and March,2022 were included in the study. Demographic data, comorbidities, treatments, length of stay in intensive care and hospital, and laboratory parameters were evaluated. According to our hospital's reference ranges, RDW value over 16% and troponin value over 15ng/L were defined as high value. Patients with both troponin value over 15ng/L and RDW value over 16% were considered to have high TR. Results: In the study, when the values checked at the time of discharge/before discharge were examined, it was seen that the intubation rate was higher and the duration of mechanical ventilation was longer in patients with high troponin and TR levels. In patients with high RDW and TR values, platelet, hemoglobin and hematocrit values were lower before discharge/discharge compared to those with low RDW and TR values. Conclusion: In our study, it was found that the intubation rate was higher and mechanical ventilation durations were longer in patients with elevated troponin and TR. We are of the opinion that early intubation practices applied in our clinic for patients with high TR and desaturation are reduced mortality.