Clinical outcomes of neoadjuvant chemoradiotherapy followed by total mesorectal excision in locally advanced rectal cancer with mesorectal fascia involvement

Jeong Ha Lee, Na-Young Kim, J. Yu, G. Yoo, Hee Chul Park, Woohyun Lee, S. Yun, H. Kim, Y. Cho, J. Huh, Y. Park, Jungwook Shin, Joon Oh Park, Seung-Tae Kim, Young Suk Park, Jeeyun Lee, Won-Ki Kang
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Abstract

Purpose: For the treatment of locally advanced rectal cancer (LARC), research on primary lesions with mesorectal fascia (MRF) involvement is lacking. This study analyzed the clinical outcomes and efficacy of dose-escalated neoadjuvant concurrent chemoradiotherapy (NCRT) to patients with LARC involving MRF.
局部晚期直肠癌伴直肠系膜筋膜受累者接受新辅助化放疗和全直肠系膜切除术的临床疗效
目的:对于局部晚期直肠癌(LARC)的治疗,缺乏对直肠间筋膜(MRF)受累的原发病灶的研究。本研究分析了剂量递增的新辅助同期化放疗(NCRT)对累及MRF的LARC患者的临床结果和疗效。
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