Qualitative Investigation and Screening of Antimicrobial Activity of Stem Extract of Clerodendrum Infortunatum Plant

Dipendra Singh, Rita Saini, Shivanand Patil
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Abstract

Clerodendrum infortunatum is also known as hill glory bower. Clerodendrum infortunatum plants are widely distributed throughout the whole world. Up to now, many species of C. infortunatum have been described in various indigenous systems of medicine that are used in preparation of folklore medicines for the treatment of various life-threatening disease, and more of the Clerodendrum infortunatum have been very well studied for their chemical constituents and biological activities It also used in Unani, Ayurveda, and siddha system of medicine for many years. In the Clerodendrum Infortunatum many compounds, including monoterpentine and its derivatives, sesquiterpene, di-terpenoids, tri-terpentine, flavonoid, quercetin, acacetin, gallic acid, sterols and flavonoid glycoside, phenylethanoid glycoside, steroids and steroid glycosides, cyclohexylethanoids, anthraqunine, cyanogenic glycosides, and others have been isolated and identified. In the present study, Chloroform, pet.ether, and water stem extract Clerodendrum infortunatum obtained by Soxhlet extraction was screened to detect the presence or absence of several bioactive compounds which are reported to cure different diseases. Anti-microbial analysis of stem extract was carried out against lacto-bacillus, E.coli and staphylococcus aureus organisms by agar well diffusion method.It was observed that the zone was recorded against this organism. The results indicates that the chloroform, pet.ether and water extract of C. infortunatum is having anti- microbial efficiency in controlling the microorganisms. So, clerodendrum infortunatum is the plant which are benificial on human health.
红花檵木茎提取物抗菌活性的定性研究与筛选
Clerodendrum infortunatum 又名山荣花。红花檵木广泛分布于世界各地。迄今为止,在各种本土医学体系中都描述了许多红花檵木的种类,这些种类被用于配制治疗各种危及生命的疾病的民间药物,红花檵木的化学成分和生物活性也得到了很好的研究。在红花檵木中已分离并鉴定出许多化合物,包括单萜及其衍生物、倍半萜、二萜、三萜、黄酮、槲皮素、醋酸苷、没食子酸、甾醇和黄酮苷、苯乙醇苷、甾体和甾体苷、环己基乙醇苷、蒽醌、氰苷等。在本研究中,通过索氏提取法对氯仿、石油醚和水提取物进行了筛选,以检测是否存在几种生物活性化合物,据报道这些化合物可治疗不同的疾病。通过琼脂井扩散法,对茎提取物进行了抗乳酸杆菌、大肠杆菌和金黄色葡萄球菌微生物分析。结果表明,红豆杉的氯仿、石油醚和水提取物具有抗微生物的功效。因此,红豆杉是一种有益于人类健康的植物。
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