Seroprevalence of Zika virus in pregnant women in Brazil: a cohort study in the macroregion of Dourados - Mato Grosso do Sul

Revista Eletrônica Acervo Saúde Pub Date : 2024-06-15 DOI:10.25248/reas.e17324.2024

Cristiane de Sá Dan, G. T. Brito, Julio Croda, A. Koishi, Claudia Nunes Duarte dos Santos, Kelle Cristhiane Soria Vieira Benedetti, S. Marchioro, Simone Simionatto

{"title":"Seroprevalence of Zika virus in pregnant women in Brazil: a cohort study in the macroregion of Dourados - Mato Grosso do Sul","authors":"Cristiane de Sá Dan, G. T. Brito, Julio Croda, A. Koishi, Claudia Nunes Duarte dos Santos, Kelle Cristhiane Soria Vieira Benedetti, S. Marchioro, Simone Simionatto","doi":"10.25248/reas.e17324.2024","DOIUrl":null,"url":null,"abstract":"Objective: Estimate the seroprevalence of Zika virus in pregnant women in the macroregion of Dourados - MS. Methods: Pregnant women admitted to the Tertiary Hospital from January 2016 to December 2017 were selected, and a serological diagnosis was made using the antibody neutralization technique for the quantification of antibodies against ZIKV with Operetta high-performance image analysis system (PerkinElmer). The study was approved by the Research Ethics Committee. Results: 100 samples were analyzed, and the prevalence of identified ZIKV was 2%. Myalgia and ostealgia (90%) and high fever (75%) were the most common symptoms. Moreover, >50% of the cases reported a regular use of repellents. Maternal ZIKV infection was associated with premature childbirth and Inter-Atrial Communication but not with neurological alterations. Conclusion: These results demonstrated the importance and need for creating public policies to mitigate the possibility of damage caused by ZIKV, raising awareness among pregnant women regarding the use of repellents and other forms prevention, such as combating vectors, and investing the availability of new ZIKV vaccines.","PeriodicalId":508106,"journal":{"name":"Revista Eletrônica Acervo Saúde","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Eletrônica Acervo Saúde","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25248/reas.e17324.2024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: Estimate the seroprevalence of Zika virus in pregnant women in the macroregion of Dourados - MS. Methods: Pregnant women admitted to the Tertiary Hospital from January 2016 to December 2017 were selected, and a serological diagnosis was made using the antibody neutralization technique for the quantification of antibodies against ZIKV with Operetta high-performance image analysis system (PerkinElmer). The study was approved by the Research Ethics Committee. Results: 100 samples were analyzed, and the prevalence of identified ZIKV was 2%. Myalgia and ostealgia (90%) and high fever (75%) were the most common symptoms. Moreover, >50% of the cases reported a regular use of repellents. Maternal ZIKV infection was associated with premature childbirth and Inter-Atrial Communication but not with neurological alterations. Conclusion: These results demonstrated the importance and need for creating public policies to mitigate the possibility of damage caused by ZIKV, raising awareness among pregnant women regarding the use of repellents and other forms prevention, such as combating vectors, and investing the availability of new ZIKV vaccines.

查看原文本刊更多论文

巴西孕妇的寨卡病毒血清流行率：南马托格罗索州杜拉多斯大区的一项队列研究

目的估算多拉多斯大区孕妇的寨卡病毒血清流行率。方法：选取2016年1月至2017年12月期间在三甲医院住院的孕妇，采用抗体中和技术对其进行血清学诊断，用Operetet定量检测寨卡病毒抗体：选取2016年1月至2017年12月在三甲医院住院的孕妇，使用Operetta高性能图像分析系统（PerkinElmer）的抗体中和技术对ZIKV抗体进行定量分析，并进行血清学诊断。该研究获得了研究伦理委员会的批准。研究结果共分析了 100 份样本，发现 ZIKV 感染率为 2%。肌痛和骨痛（90%）以及高烧（75%）是最常见的症状。此外，50%以上的病例报告说经常使用驱虫剂。产妇感染 ZIKV 与早产和房室间通信有关，但与神经系统改变无关。结论这些结果表明，制定公共政策以减少 ZIKV 可能造成的损害、提高孕妇对使用驱虫剂和其他预防形式（如打击病媒）的认识以及投资于新型 ZIKV 疫苗的可用性，是非常重要和必要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Revista Eletrônica Acervo Saúde

自引率

0.00%

发文量