Structure of the poxvirus core

IF 12.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Structural & Molecular Biology Pub Date : 2024-06-18 DOI:10.1038/s41594-024-01331-5

Fasséli Coulibaly

引用次数: 0

Abstract

Poxviruses range from deadly smallpox to attenuated vaccinia virus used in vaccines and oncolytic vectors. Despite their broad, if antithetical, effects on humankind, the mechanistic details of poxvirus assembly are not known. Here we discuss advances in revealing the structure of the palisade layer which underlies the viral core morphology.

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痘病毒核心的结构

痘病毒的种类繁多，既有致命的天花病毒，也有用于疫苗和溶瘤载体的减毒疫苗病毒。尽管痘病毒对人类有着广泛的影响，甚至是对立的影响，但人们对痘病毒的组装机理却知之甚少。在此，我们将讨论在揭示作为病毒核心形态基础的栅栏层结构方面取得的进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Structural & Molecular Biology BIOCHEMISTRY & MOLECULAR BIOLOGY-BIOPHYSICS

CiteScore

22.00

自引率

1.80%

发文量

160

审稿时长

3-8 weeks

期刊介绍： Nature Structural & Molecular Biology is a comprehensive platform that combines structural and molecular research. Our journal focuses on exploring the functional and mechanistic aspects of biological processes, emphasizing how molecular components collaborate to achieve a particular function. While structural data can shed light on these insights, our publication does not require them as a prerequisite.