EBV-Related Lymphoproliferative Diseases: A Review in Light of New Classifications.

IF 2 4区医学 Q3 HEMATOLOGY

Mediterranean Journal of Hematology and Infectious Diseases Pub Date : 2024-05-01 eCollection Date: 2024-01-01 DOI:10.4084/MJHID.2024.042

Pietro Tralongo, Arianna Bakacs, Luigi Maria Larocca

引用次数: 0

Abstract

Epstein-Barr virus (EBV) is a prevalent virus that can be detected in the vast majority of the population. Most people are asymptomatic and remain chronically infected throughout their lifetimes. However, in some populations, EBV has been linked to a variety of B-cell lymphoproliferative disorders (LPDs), such as Burkitt lymphoma, classic Hodgkin lymphoma, and other LPDs. T-cell LPDs have been linked to EBV in part of peripheral T-cell lymphomas, angioimmunoblastic T-cell lymphomas, extranodal nasal natural killer/T-cell lymphomas, and other uncommon histotypes. This article summarizes the current evidence for EBV-associated LPDs in light of the upcoming World Health Organization classification and the 2022 ICC classification.

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EBV相关淋巴组织增生性疾病：根据新的分类进行回顾。

Epstein-Barr 病毒（EBV）是一种流行性病毒，可在绝大多数人群中检测到。大多数人没有症状，终生处于慢性感染状态。然而，在某些人群中，EB 病毒与各种 B 细胞淋巴增生性疾病（LPDs）有关，如伯基特淋巴瘤、典型霍奇金淋巴瘤和其他 LPDs。T细胞淋巴增生性疾病与EBV有关的部分病例包括外周T细胞淋巴瘤、血管免疫母细胞T细胞淋巴瘤、结节外鼻腔自然杀伤/T细胞淋巴瘤以及其他不常见的组织类型。本文根据即将发布的世界卫生组织分类和 2022 年国际协调委员会分类，总结了目前与 EBV 相关的 LPD 的证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Mediterranean Journal of Hematology and Infectious Diseases Medicine-Hematology

CiteScore

4.20

自引率

6.20%

发文量

113

审稿时长

12 weeks

期刊介绍： Reciprocal interdependence between infectious and hematologic diseases (malignant and non-malignant) is well known. This relationship is particularly evident in Mediterranean countries. Parasitosis as Malaria, Leishmaniosis, B Hookworms, Teniasis, very common in the southeast Mediterranean area, infect about a billion people and manifest prevalently with anemia so that they are usually diagnosed mostly by experienced hematologist on blood or bone marrow smear. On the other hand, infections are also a significant problem in patients affected by hematological malignancies. The blood is the primary vector of HIV infection, which otherwise manifest with symptoms related to a reduction in T lymphocytes. In turn, infections can favor the insurgency of hematological malignancies. The causative relationship between Epstein-Barr virus infection, Helicobacter pylori, hepatitis C virus, HIV and lymphoproliferative diseases is well known.