Oral herpes simplex virus infection in patients undergoing chemotherapy - an integrative review.

IF 1.7 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

GMS Hygiene and Infection Control Pub Date : 2024-05-17 eCollection Date: 2024-01-01 DOI:10.3205/dgkh000483

Aristéa Ribeiro Carvalho, Renan Lemos da Silva, Ed Campos Vieira Neto, Mailon Cury Carneiro, Ana Carolina Fragoso Motta, Ana Paula Campanelli, Cassia Maria Fischer Rubira, Paulo Sérgio da Silva Santos

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Abstract

Aim: The purpose of this study is to undertake an integrative literature review in order to determine the prevalence, etiology, and reactivation of oral HSV infection in patients receiving chemotherapy (CT).

Methods: The study was carried out in the PubMed/MEDLINE, Embase, Virtual Health Library, and Scopus databases, using the descriptors "Herpes Simplex", "Viral Diseases", "Mouth", and "Antineoplastic Agents".

Results: The findings suggest that HSV infection is widespread in this group of patients and can be severe. HSV infection is frequent in CT patients, and treatment should begin as soon as it is feasible, utilizing antivirals to avoid future difficulties, as patients are immunocompromised.

Conclusion: It is critical for health professionals to be fully informed on the dangers and treatment choices available, with the most appropriate therapy for each circumstance. Furthermore, more recent research with acceptable methodological rigor is required to better quantify the prevalence of HSV in these patients.

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化疗患者的口腔单纯疱疹病毒感染--综述。

目的：本研究旨在进行综合文献综述，以确定接受化疗（CT）的患者口腔 HSV 感染的流行率、病因和再激活情况：研究在 PubMed/MEDLINE、Embase、Virtual Health Library 和 Scopus 数据库中进行，使用的描述符为 "单纯疱疹"、"病毒性疾病"、"口腔 "和 "抗肿瘤药物"：结果：研究结果表明，HSV 感染在这类患者中很普遍，而且可能很严重。由于患者免疫力低下，CT 患者中常有 HSV 感染，因此应尽快开始治疗，并使用抗病毒药物，以避免日后出现困难：医护人员必须充分了解疾病的危害和治疗方法，并根据具体情况选择最合适的疗法。此外，为了更好地量化 HSV 在这些患者中的流行情况，还需要更多方法严谨的最新研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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GMS Hygiene and Infection Control PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

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审稿时长

10 weeks