Enfortumab vedotin and pembrolizumab combination as a relevant game changer in urothelial carcinoma: What is left behind?

IF 12.8 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

Med Pub Date : 2024-06-14 DOI:10.1016/j.medj.2024.04.006

Joaquim Bellmunt, Rosa Nadal

引用次数: 0

Abstract

The EV-302 study¹ marks a pivotal leap in the management of advanced urothelial carcinoma, setting a new benchmark for frontline therapy. Enfortumab vedotin plus pembrolizumab is the first combination therapy that has ever outperformed standard chemotherapy. The degree of benefit and the reported safety profile should make this combination a first-choice option for most patients with advanced-stage urothelial carcinoma.

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恩福单抗维多汀和 pembrolizumab 联合疗法改变了尿路上皮癌的治疗方式：还有什么可留恋的？

EV-302 研究1 标志着晚期尿路上皮癌治疗的一次关键性飞跃，为一线治疗树立了新的标杆。Enfortumab vedotin+pembrolizumab 是首个疗效优于标准化疗的联合疗法。这种联合疗法的获益程度和所报告的安全性应使其成为大多数晚期尿路上皮癌患者的首选疗法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Med MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

17.70

自引率

0.60%

发文量

102

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