Cu(II)/PTABS-Promoted, Chemoselective Amination of HaloPyrimidines

IF 3.3 2区化学 Q1 CHEMISTRY, ORGANIC

The Journal of Organic Chemistry Pub Date : 2024-06-15 DOI:10.1021/acs.joc.4c00171

Vikram Phulwale, Harshita Shet, Krishna Chaitanya Gunturu, Smruti Rekha Rout, Rambabu Dandela, Suyog Adhav and Anant R. Kapdi*,

引用次数: 0

Abstract

Chemoselective amination is a highly desired synthetic methodology, given its importance as a possible strategy to synthesize various drug molecules and agrochemicals. We, herein, disclose a highly chemoselective Cu(II)-PTABS-promoted amination of pyrimidine structural feature containing different halogen atoms.

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Cu(II)/PTABS 促进的卤代嘧啶化学选择性胺化。

化学选择性胺化是一种非常需要的合成方法，因为它是合成各种药物分子和农用化学品的重要策略。我们在此揭示了一种高度化学选择性的 Cu(II)-PTABS 促进的含有不同卤素原子的嘧啶结构特征的胺化反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

The Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： The Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.