Duration of severe and moderate symptoms in pharyngitis by cause

IF 1.8 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Ana Moragas , Carolina Sarvisé , Frederic Gómez , Ester Picó-Plana , Silvia Crispi , Carl Llor
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引用次数: 0

Abstract

Objective

This study aimed to assess the cause of acute pharyngitis and determine the duration of severe and moderate symptoms based on the aetiology.

Design

Prospective observational study.

Site

One urban health care centre.

Participants

Patients aged 15 or older with acute pharyngitis were included.

Interventions

Bacterial identification was carried out in the microbiology lab using MALDI-TOF in two throat samples. Patients received a symptom diary to return after one week.

Main measurements

Number of days with severe symptoms, scoring 5 or more in any of the symptoms included in the symptom diary, and moderate symptoms, scoring 3 or more.

Results

Among the 149 patients recruited, beta-haemolytic streptococcus group A (GABHS) was the most common aetiology. Symptoms and signs alone as well as the mean Centor score cannot distinguish between GABHS and other bacterial causes in patients with acute pharyngitis. However, there was a trend indicating that infections caused by Streptococcus dysgalactiae and Streptococcus agalactiae presented more severe symptoms, whereas infections attributed to the Streptococcus anginosus group, Fusobacterium spp., and those where oropharyngeal microbiota was isolated tended to have milder symptoms. S. dysgalactiae infections showed a trend towards longer severe and moderate symptom duration.

Conclusion

GABHS was the most prevalent, but group C streptococcus caused more severe and prolonged symptoms.

按病因分列的咽炎重度和中度症状持续时间。
研究目的本研究旨在评估急性咽炎的病因,并根据病因确定重度和中度症状的持续时间:前瞻性观察研究。地点:一家城市医疗中心:一家城市医疗中心:干预措施:干预措施:在微生物实验室使用 MALDI-TOF 对两份咽喉样本进行细菌鉴定。患者一周后将收到一份症状日记:主要测量指标:出现严重症状(症状日记中的任何症状达到或超过 5 分)和中度症状(症状日记中的任何症状达到或超过 3 分)的天数:在招募的 149 名患者中,最常见的病因是 A 组溶血性链球菌(GABHS)。在急性咽炎患者中,仅凭症状和体征以及平均 Centor 评分无法区分 GABHS 和其他细菌病因。不过,有一种趋势表明,由痢疾链球菌和无乳链球菌引起的感染症状更严重,而由鹅口疮链球菌、镰刀菌属和口咽微生物群引起的感染症状往往较轻。痢疾杆菌感染显示出重度和中度症状持续时间较长的趋势:结论:GABHS最常见,但C组链球菌引起的症状更严重、持续时间更长。
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来源期刊
Atencion Primaria
Atencion Primaria 医学-医学:内科
CiteScore
2.90
自引率
8.00%
发文量
156
审稿时长
33 days
期刊介绍: Atención Primaria es una revista que publica trabajos de investigación relativos al ámbito de la atención primaria de salud. Desde el punto de vista conceptual, Atención Primaria asume el nuevo modelo de atención primaria de salud, orientado no sólo a la curación de la enfermedad, sino también a su prevención y a la promoción de la salud, tanto en el plano individual como en el de la familia y la comunidad. En estos nuevos aspectos que definen el modelo de atención primaria de salud es en los que se centran los trabajos de investigación que publica Atención Primaria, la primera revista de originales española creada para recoger y difundir la producción científica realizada desde los centros de atención primaria de salud sobre cuestiones como protocolización de la asistencia, programas de prevención, seguimiento y control de pacientes crónicos, organización y gestión de la asistencia primaria, entre otros.
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