Correlation not Causation: Looking Back at the History of VUR

IF 2.1 3区医学 Q2 UROLOGY & NEPHROLOGY

Urology Pub Date : 2024-11-01 DOI:10.1016/j.urology.2024.06.002

Tenny Zhang, Jeremy Wiygul

引用次数: 0

Abstract

Vesicoureteral reflux (VUR) is a medical condition where urine flows retrograde from the bladder superiorly, and has traditionally been considered a risk factor for kidney damage in children. However, over the past decade and a half, several randomized controlled trials have shown the risk of kidney damage in the presence of VUR is low, and any treatment for VUR does not change that risk. Here, we review the history of VUR as a pathologic condition, how the interpretation of that history led to possibly overestimating the danger, and how current findings should be seen in the context of that history.

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相关而非因果--回顾 VUR 的历史。

膀胱输尿管反流（VUR）是一种尿液从膀胱上端逆流而下的病症，传统上被认为是儿童肾脏受损的危险因素。然而，在过去的十五年中，多项随机对照试验表明，存在输尿管返流时肾脏受损的风险很低，而且任何治疗输尿管返流的方法都不会改变这种风险。在此，我们回顾了 VUR 作为一种病理状态的历史，对这一历史的解释如何导致可能高估了其危险性，以及应如何在这一历史背景下看待目前的研究结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Urology 医学-泌尿学与肾脏学

CiteScore

3.30

自引率

9.50%

发文量

716

审稿时长

59 days

期刊介绍： Urology is a monthly, peer–reviewed journal primarily for urologists, residents, interns, nephrologists, and other specialists interested in urology The mission of Urology®, the "Gold Journal," is to provide practical, timely, and relevant clinical and basic science information to physicians and researchers practicing the art of urology worldwide. Urology® publishes original articles relating to adult and pediatric clinical urology as well as to clinical and basic science research. Topics in Urology® include pediatrics, surgical oncology, radiology, pathology, erectile dysfunction, infertility, incontinence, transplantation, endourology, andrology, female urology, reconstructive surgery, and medical oncology, as well as relevant basic science issues. Special features include rapid communication of important timely issues, surgeon''s workshops, interesting case reports, surgical techniques, clinical and basic science review articles, guest editorials, letters to the editor, book reviews, and historical articles in urology.