Dmytro Stepanskyi, Oksana Ishchenko, Ting Luo, Francois Lebreton, Jason W Bennett, Iryna Kovalenko, Patrick McGann
{"title":"Phenotypic and genomic analysis of bacteria from war wounds in Dnipro, Ukraine.","authors":"Dmytro Stepanskyi, Oksana Ishchenko, Ting Luo, Francois Lebreton, Jason W Bennett, Iryna Kovalenko, Patrick McGann","doi":"10.1093/jacamr/dlae090","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To better understand the source and potential transmission routes of antibiotic-resistant bacteria infecting injured service members in Ukraine.</p><p><strong>Methods: </strong>Phenotypic and genomic characterizations were performed on 11 Gram-negative pathogens cultured from war wounds at an intermediate evacuation hospital in Dnipro.</p><p><strong>Results: </strong>The analysis revealed both susceptible and extensively drug-resistant strains present in cultures, including high-risk global clones carrying carbapenemases.</p><p><strong>Conclusions: </strong>Globally distributed carbapenemase-producing lineages are being acquired early in the medical evacuation process.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":null,"pages":null},"PeriodicalIF":3.7000,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11170486/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JAC-Antimicrobial Resistance","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/jacamr/dlae090","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: To better understand the source and potential transmission routes of antibiotic-resistant bacteria infecting injured service members in Ukraine.
Methods: Phenotypic and genomic characterizations were performed on 11 Gram-negative pathogens cultured from war wounds at an intermediate evacuation hospital in Dnipro.
Results: The analysis revealed both susceptible and extensively drug-resistant strains present in cultures, including high-risk global clones carrying carbapenemases.
Conclusions: Globally distributed carbapenemase-producing lineages are being acquired early in the medical evacuation process.