A new signalling-based system for germ cell reprogramming

IF 12.1 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Urology Pub Date : 2024-06-13 DOI:10.1038/s41585-024-00907-6

Maria Chiara Masone

引用次数: 0

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基于信号的生殖细胞重编程新系统

人类原始生殖细胞（hPGCs）通过表观遗传学重编程分化为有丝分裂的精原细胞和卵原细胞是发育的基本过程。hPGC类细胞（hPGCLCs）已成功地从人类多能干细胞（hPSCs）开始体外诱导，但效率低且易发生去分化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Urology 医学-泌尿学与肾脏学

CiteScore

12.50

自引率

2.60%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.