Neurotoxicology: a clinical systems-based review.

IF 2.4 Q2 CLINICAL NEUROLOGY

PRACTICAL NEUROLOGY Pub Date : 2024-09-13 DOI:10.1136/pn-2023-003983

Frederick W Vonberg, Peter G Blain

引用次数: 0

Abstract

Neurological disease caused by toxins is widespread but under-recognised. Despite increasing public interest and a growing number of novel potential neurotoxins, diagnosis of neurotoxic disease is often delayed or missed, resulting in poorer patient outcomes. This article discusses neurotoxic syndromes using a systems-based approach, focusing on environmental and occupational agents. We do not discuss recreational drugs, pharmaceutical agents or developmental neurotoxins in detail. We aim to provide neurologists with a working understanding of the scenarios in which a clinical presentation may be due to a neurotoxin and how to approach confirmation of the diagnosis.

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神经毒理学：基于临床系统的综述。

由毒素引起的神经系统疾病非常普遍，但人们对其认识不足。尽管公众对神经毒性疾病的关注与日俱增，潜在的新型神经毒素也越来越多，但神经毒性疾病的诊断往往被延误或漏诊，导致患者的治疗效果不佳。本文采用基于系统的方法讨论神经毒性综合征，重点关注环境和职业因素。我们不详细讨论娱乐性药物、药物制剂或发育神经毒素。我们的目的是让神经科医生了解在哪些情况下临床表现可能是由神经毒素引起的，以及如何进行确诊。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

PRACTICAL NEUROLOGY Medicine-Neurology (clinical)

CiteScore

3.70

自引率

3.60%

发文量

113

期刊介绍： The essential point of Practical Neurology is that it is practical in the sense of being useful for everyone who sees neurological patients and who wants to keep up to date, and safe, in managing them. In other words this is a journal for jobbing neurologists - which most of us are for at least part of our time - who plough through the tension headaches and funny turns week in and week out. Primary research literature potentially relevant to routine clinical practice is far too much for any neurologist to read, let alone understand, critically appraise and assimilate. Therefore, if research is to influence clinical practice appropriately and quickly it has to be digested and provided to neurologists in an informative and convenient way.