Utility of ultra-high-field magnetic resonance imaging in the detection and management of brain metastases

Abstract

This letter discusses the clinical utility of ultra-high field magnetic resonance imaging (MRI) at 7 Tesla (7T) for the detection and management of brain metastases. Brain metastases are the most common intracranial tumors and their early detection and management are crucial for improving patient outcomes. Conventional MRI may miss subtle lesions, and 7T provides unprecedented anatomical details with high spatial resolution and improved contrast. It allows the visualization of fine tumor structures and margins, as well as early infiltration and angiogenesis. Techniques such as susceptibility-weighted imaging and quantitative susceptibility mapping exploit the 7T increased sensitivity to magnetic susceptibility effects, facilitating the detection of additional small or hemorrhagic lesions. Advanced methods have also provided novel neuroimaging biomarkers that characterize neuroinflammation and neurovascular changes. While acknowledging limitations including cost and technical challenges, earlier detection and targeted treatment informed by 7T MRI insights could minimize brain metastasis damage and improve patient outcomes.