Developing technologies to assess vascular ageing: a roadmap from VascAgeNet.

IF 2.3 4区医学 Q3 BIOPHYSICS

Physiological measurement Pub Date : 2024-06-05 DOI:10.1088/1361-6579/ad548e

Serena Zanelli, Davide Agnoletti, Jordi Alastruey, John Allen, Elisabetta Bianchini, Vasiliki Bikia, Pierre Boutouyrie, Rosa Maria Bruno, Rachel Climie, Djeldjli Djamaleddine, Eugenia Gkaliagkousi, Alessandro Giudici, Kristina Gopcevic, Andrea Grillo, Andrea Guala, Bernhard Hametner, Jayaraj Joseph, Parmis Karimpour, Vimarsha Kodithuwakku, Panayiotis A Kyriacou, Antonios Lazaridis, Mai Tone Lonnebakken, Maria Raffaella Martina, Christopher Clemens Mayer, P M Nabeel, Petras Navickas, Janos Nemcsik, Stefan Orter, Chloe Park, Telmo Pereira, Giacomo Pucci, Ana Belen Amado Rey, Paolo Salvi, Ana Carolina Gonçalves Seabra, Ute Seeland, Thomas van Sloten, Bart Spronck, Gerard Stansby, Indra Steens, Thomas Stieglitz, Isabella Tan, Dave Veerasingam, Siegfried Wassertheurer, Thomas Weber, Berend E Westerhof, Peter H Charlton

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引用次数: 0

Abstract

Vascular ageing is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk, with potential applications in disease diagnosis and prognosis, and for guiding treatments. However, vascular ageing is not yet routinely assessed in clinical practice. A key step towards this is the development of technologies to assess vascular ageing. In this Roadmap, experts discuss several aspects of this process, including: measurement technologies; the development pipeline; clinical applications; and future research directions. The Roadmap summarises the state of the art, outlines the major challenges to overcome, and identifies potential future research directions to address these challenges.

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开发评估血管老化的技术：VascAgeNet 的路线图。

血管老化是指动脉结构和功能的退化，随着年龄的增长而自然发生，也可因疾病而加速。对血管老化的测量正在成为心血管风险的标志，并有可能应用于疾病诊断、预后和指导治疗。然而，血管老化尚未在临床实践中得到常规评估。实现这一目标的关键一步是开发评估血管老化的技术。在本路线图中，专家们讨论了这一过程的几个方面，包括：测量技术、开发流水线、临床应用和未来研究方向。路线图总结了目前的技术水平，概述了需要克服的主要挑战，并确定了应对这些挑战的潜在未来研究方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Physiological measurement 生物-工程：生物医学

CiteScore

5.50

自引率

9.40%

发文量

124

审稿时长

3 months

期刊介绍： Physiological Measurement publishes papers about the quantitative assessment and visualization of physiological function in clinical research and practice, with an emphasis on the development of new methods of measurement and their validation. Papers are published on topics including: applied physiology in illness and health electrical bioimpedance, optical and acoustic measurement techniques advanced methods of time series and other data analysis biomedical and clinical engineering in-patient and ambulatory monitoring point-of-care technologies novel clinical measurements of cardiovascular, neurological, and musculoskeletal systems. measurements in molecular, cellular and organ physiology and electrophysiology physiological modeling and simulation novel biomedical sensors, instruments, devices and systems measurement standards and guidelines.