{"title":"Comparison of linear energy transfer measurement for therapeutic carbon beam using CR-39 and TLD.","authors":"Zhou Yuan, Weihai Zhuo, Shiyan Yang, Zhiling Li, Jingfang Zhao, Bo Chen","doi":"10.1088/1361-6498/ad53d9","DOIUrl":null,"url":null,"abstract":"<p><p>The measurement of linear energy transfer (LET) is crucial for the evaluation of the radiation effect in heavy ion therapy. As two detectors which are convenient to implant into the phantom, the performance of CR-39 and thermoluminescence detector (TLD) for LET measurement was compared by experiment and simulation in this study. The results confirmed the applicability of both detectors for LET measurements, but also revealed that the CR-39 detector would lead to potential overestimation of dose-averaged LET compared with the simulation by PHITS, while the TLD would have a large uncertainty measuring ions with LET larger than 20 keV<i>μ</i>m<sup>-1</sup>. The results of this study were expected to improve the detection method of LET for therapeutic carbon beam and would finally be benefit to the quality assurance of heavy ion radiotherapy.</p>","PeriodicalId":50068,"journal":{"name":"Journal of Radiological Protection","volume":" ","pages":""},"PeriodicalIF":1.4000,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Radiological Protection","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1088/1361-6498/ad53d9","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
The measurement of linear energy transfer (LET) is crucial for the evaluation of the radiation effect in heavy ion therapy. As two detectors which are convenient to implant into the phantom, the performance of CR-39 and thermoluminescence detector (TLD) for LET measurement was compared by experiment and simulation in this study. The results confirmed the applicability of both detectors for LET measurements, but also revealed that the CR-39 detector would lead to potential overestimation of dose-averaged LET compared with the simulation by PHITS, while the TLD would have a large uncertainty measuring ions with LET larger than 20 keVμm-1. The results of this study were expected to improve the detection method of LET for therapeutic carbon beam and would finally be benefit to the quality assurance of heavy ion radiotherapy.
线性能量传递（LET）的测量对于评估重离子治疗中的辐射效应至关重要。CR-39 和热释光探测器（TLD）是两种便于植入人体模型的探测器，本研究通过实验和模拟比较了这两种探测器在 LET 测量中的性能。结果证实了这两种探测器在 LET 测量中的适用性，但也发现与 PHITS 的模拟结果相比，CR-39 探测器可能会导致剂量平均 LET 被高估，而 TLD 在测量 LET 大于 20 keV μm-1 的离子时会有很大的不确定性。这项研究的结果有望改进治疗用碳束的 LET 检测方法，最终有利于重离子放射治疗的质量保证。
期刊介绍：
Journal of Radiological Protection publishes articles on all aspects of radiological protection, including non-ionising as well as ionising radiations. Fields of interest range from research, development and theory to operational matters, education and training. The very wide spectrum of its topics includes: dosimetry, instrument development, specialized measuring techniques, epidemiology, biological effects (in vivo and in vitro) and risk and environmental impact assessments.
The journal encourages publication of data and code as well as results.
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