A mobile home for T cells

IF 37.2 1区材料科学 Q1 CHEMISTRY, PHYSICAL

Nature Materials Pub Date : 2024-06-04 DOI:10.1038/s41563-024-01906-z

Kewen Lei, Darrell J. Irvine

引用次数: 0

Abstract

Lyophilized lymph nodes are a natural scaffold to deliver chimeric antigen receptor (CAR) T cells to tumour resection sites, where they serve as a natural T cell-supporting niche and enhance CAR T cell efficacy in reducing recurrence in preclinical tumour resection models.

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T 细胞的移动家园

冻干淋巴结是将嵌合抗原受体（CAR）T 细胞输送到肿瘤切除部位的天然支架，淋巴结可作为天然的 T 细胞支持龛位，提高 CAR T 细胞在临床前肿瘤切除模型中减少复发的功效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Materials 工程技术-材料科学：综合

CiteScore

62.20

自引率

0.70%

发文量

221

审稿时长

3.2 months

期刊介绍： Nature Materials is a monthly multi-disciplinary journal aimed at bringing together cutting-edge research across the entire spectrum of materials science and engineering. It covers all applied and fundamental aspects of the synthesis/processing, structure/composition, properties, and performance of materials. The journal recognizes that materials research has an increasing impact on classical disciplines such as physics, chemistry, and biology. Additionally, Nature Materials provides a forum for the development of a common identity among materials scientists and encourages interdisciplinary collaboration. It takes an integrated and balanced approach to all areas of materials research, fostering the exchange of ideas between scientists involved in different disciplines. Nature Materials is an invaluable resource for scientists in academia and industry who are active in discovering and developing materials and materials-related concepts. It offers engaging and informative papers of exceptional significance and quality, with the aim of influencing the development of society in the future.