The relationship between schizophrenia or schizoaffective disorder and type 1 diabetes mellitus: a scoping review of observational studies.

IF 1.1 Q4 PSYCHIATRY

NEUROPSYCHIATRIE Pub Date : 2024-06-04 DOI:10.1007/s40211-024-00499-y

Yi-Chun Liu, Yin-To Liao, Kuan-Han Lin

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引用次数: 0

Abstract

Objective: Both schizophrenia and type 1 diabetes mellitus (T1D) are known as immune-related disorders. We systematically reviewed observational studies to explore the relationship between schizophrenia or schizoaffective disorder and T1D.

Methods: A preliminary search of articles was completed using the following databases: Airiti Library, CINAHL Complete (via EBSCOhost), OVID MEDLINE, Embase, and PubMed. Two researchers independently assessed each study's quality based on Joanna Briggs Institute (JBI). A narrative review summarized the potential relationship between the two diseases.

Results: Eleven studies were included in the final analysis. Six observational studies investigated the risk of schizophrenia and schizoaffective disorder in patients with T1D. Two studies showed negative correlations, one showed no correlation, and three showed positive correlations. On the other hand, five studies reported the prevalence of T1D in patients with schizophrenia. Two of them showed positive associations, and three others showed no association. Although the majority of the included studies suggested a positive association between the two medical conditions, these studies were still too heterogeneous to draw consistent results.

Conclusion: We found conflicting results regarding the bidirectional relationship between schizophrenia or schizoaffective disorder and T1D. These may stem from differences in study design, sampling methods, or definition of diagnoses, which are essential aspects to consider in future research.

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精神分裂症或分裂情感障碍与 1 型糖尿病之间的关系：观察性研究的范围界定综述。

目的：精神分裂症和1型糖尿病（T1D）都是众所周知的免疫相关疾病。我们对观察性研究进行了系统回顾，以探讨精神分裂症或精神分裂情感障碍与 T1D 之间的关系：我们使用以下数据库对文章进行了初步检索：Airiti图书馆、CINAHL Complete（通过EBSCOhost）、OVID MEDLINE、Embase和PubMed。两名研究人员根据乔安娜-布里格斯研究所（JBI）对每项研究的质量进行了独立评估。一篇叙述性综述总结了两种疾病之间的潜在关系：最终分析纳入了 11 项研究。六项观察性研究调查了T1D患者罹患精神分裂症和精神分裂情感障碍的风险。其中两项研究结果呈负相关，一项研究结果无相关性，三项研究结果呈正相关。另一方面，有五项研究报告了 T1D 在精神分裂症患者中的患病率。其中两项研究表明两者呈正相关，另外三项研究表明两者之间没有关联。尽管纳入的大多数研究表明这两种病症之间存在正相关，但这些研究仍然过于分散，无法得出一致的结果：我们发现，精神分裂症或精神分裂情感障碍与 T1D 之间的双向关系存在相互矛盾的结果。结论：我们发现精神分裂症或精神分裂情感障碍与 T1D 的双向关系存在相互矛盾的结果，这可能源于研究设计、抽样方法或诊断定义的差异，这些都是未来研究中需要考虑的重要方面。

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来源期刊

NEUROPSYCHIATRIE PSYCHIATRY-

CiteScore

3.80

自引率

20.00%

发文量

期刊介绍： Die Zeitschrift ist das offizielle Organ der „Österreichischen Gesellschaft für Psychiatrie, Psychotherapie und Psychosomatik (ÖGPP)'', und wissenschaftliches Organ der Österreichischen Alzheimer Gesellschaft, der Österreichischen Gesellschaft für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie, der Österreichischen Schizophreniegesellschaft, und der pro mente austria - Österreichischer Dachverband der Vereine und Gesellschaften für psychische und soziale Gesundheit.Sie veröffentlicht Übersichten zu relevanten Themen des Fachs, Originalarbeiten, Kasuistiken sowie Briefe an die Herausgeber. Zudem wird auch Buchbesprechungen sowie Neuigkeiten aus den Bereichen Personalia, Standes- und Berufspolitik sowie Kongressankündigungen Raum gewidmet.Thematisch ist das Fach Psychiatrie und die Methoden der Psychotherapie in allen ihren Facetten vertreten. Die Zeitschrift richtet sich somit an alle Berufsgruppen, die sich mit Ursachen, Erscheinungsformen und Behandlungsmöglichkeiten von psychischen Störungen beschäftigen. -----------------------------------------------------------------------------------------------------· The professional and educational journal of the Austrian Society of Psychiatry, Psychotherapy and Psychosomatics (Österreichische Gesellschaft für Psychiatrie, Psychotherapie und Psychosomatik; ÖGPP) and the Austrian Society of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy (Österreichische Gesellschaft für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie; ÖGKJP)· Overviews of all relevant topics pertaining to the discipline· Intended for all occupational groups committed to the causes and manifestations of, as well as therapy options for psychic disorders· All manuscripts principally pass through a double-blind peer review process involving at least two independent expertsThe official journal of the Austrian Societies of Psychiatry, Psychotherapy and Psychosomatics (ÖGPP) and Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy (ÖGKJP)The journal publishes overviews of relevant issues in the field, original work, case reports and letters to the editors. In addition, space is devoted to book reviews, news from the areas of personnel matters and professional policies, and conference announcements.Thematically, the discipline of psychiatry and the methods of psychotherapy are represented in all their facets. The journal is thus aimed at all professional groups committed to the causes and manifestations of, as well as therapy options for psychic disorders