Heatstroke Comorbid with SARS-CoV-2 Infection: A Case Report and Literature Review.

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL

International Medical Case Reports Journal Pub Date : 2024-05-30 eCollection Date: 2024-01-01 DOI:10.2147/IMCRJ.S461078

Xiao-Xiao Ni, Zhe-Ying Liu, Yan-Yan Zeng, Zhi-Feng Liu

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引用次数: 0

Abstract

Background: Hyperthermia and multiple organ dysfunction syndrome (MODS) are the main characteristics of heatstroke and COVID-19. Differentiating between these illnesses is crucial during a summer COVID-19 pandemic, but cases of heatstroke comorbid with COVID-19 are rarely reported.

Case description: We report the first case of heatstroke comorbid with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in a 52-year-old male. After receiving intravenous antibiotics, organ protection measures, and treatment for coagulation disorders, his fever and coma resolved. However, he developed dyspnea and cerebral hemorrhage after several days. This patient experienced a multi-pathogen pulmonary infection and an intractable coagulopathy that ultimately resulted in MODS and death.

Conclusion: The combination of heatstroke and SARS-CoV-2 infection exacerbated inflammation, immune abnormalities, and coagulation disorders. The interaction between inflammation and coagulation disturbances contributed to the underlying mechanism in this case, highlighting the importance of early anti-infection, treatment for coagulopathy, immune regulation, and organ protection as crucial interventions.

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中暑并发 SARS-CoV-2 感染：病例报告与文献综述

背景：高热和多器官功能障碍综合征（MODS）是中暑和 COVID-19 的主要特征。在夏季 COVID-19 大流行期间，区分这两种疾病至关重要，但中暑合并 COVID-19 的病例却鲜有报道：我们报告了第一例中暑合并严重急性呼吸系统综合征冠状病毒 2（SARS-CoV-2）感染的病例，患者是一名 52 岁的男性。在接受静脉注射抗生素、器官保护措施和凝血功能障碍治疗后，他的发烧和昏迷症状缓解。然而，几天后他又出现了呼吸困难和脑出血。该患者经历了多种病原体的肺部感染和难治性凝血病，最终导致 MODS 和死亡：结论：中暑和 SARS-CoV-2 感染共同加剧了炎症、免疫异常和凝血功能障碍。炎症和凝血功能障碍之间的相互作用是本病例的潜在机制，突出了早期抗感染、凝血功能障碍治疗、免疫调节和器官保护作为关键干预措施的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Medical Case Reports Journal MEDICINE, GENERAL & INTERNAL-

CiteScore

1.40

自引率

0.00%

发文量

135

审稿时长

16 weeks

期刊介绍： International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.