Endoscopic ultrasound-guided fine-needle aspiration in the diagnostic value of focal liver lesions: A systematic analysis of 88 cases (with video)

IF 2.6 4区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Clinics and research in hepatology and gastroenterology Pub Date : 2024-05-31 DOI:10.1016/j.clinre.2024.102382

Xiaohong Kong , Zijun Fan , Ruiping Li , Duanmin Hu , Guilian Cheng

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引用次数: 0

Abstract

Background and aims

Endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) is an important diagnostic tool for suspected parenchymal lesions in the gastrointestinal tract and adjacent organs. Our study aimed to evaluate the safety and effectiveness of EUS-FNA in focal liver lesions (FLLs).

Method

Data from 88 patients diagnosed with FLLs by imaging who underwent EUS-FNA from 1 January 2017 to 31 August 2022 were reviewed in our retrospective study at the Second Affiliated Hospital of Soochow University and Ruijin Hospital of the School of Medicine of Shanghai Jiao Tong University. The EUS-FNA biopsy results were compared with the final diagnosis to evaluate diagnostic value. The relevant factors were analysed to determine their influence on EUS-FNA biopsy results.

Results

The 88 patients analysed in this study resulted in a final diagnosis of 86 malignant and two benign cases. The overall diagnostic accuracy of EUS-FNA in FLLs was 93.18 % (82/88; 95 % Confidence Interval [CI], 87.9–98.5), with a sensitivity, specificity, positive predictive value, and negative predictive value of 93.02 % (80/86; 95 %CI, 87.6–98.4), 100 % (2/2; 95 %CI, 100–100), 100 % (80/80; 95 %CI, 100–100), and 25 % (2/8; 95 %CI, -5–55.0), respectively. The parameters related to lesion and procedure were not significantly different between these two groups (p > 0.05). The number of puncture needles in the groups showed a statistically significant difference between multiple and single punctures (p = 0.001).

Conclusion

Our data revealed that EUS-FNA is a safe and reliable diagnostic method for FLLs that shows high accuracy.

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文章标题全文：内镜超声引导下细针抽吸术在肝脏病灶诊断中的价值：88 例病例的系统分析（附视频）。

背景和目的：内镜超声引导下细针抽吸术（EUS-FNA）是诊断胃肠道和邻近器官疑似实质性病变的重要工具。我们的研究旨在评估 EUS-FNA 在肝脏局灶性病变（FLLs）中的安全性和有效性：我们的回顾性研究回顾了苏州大学附属第二医院和上海交通大学医学院附属瑞金医院在2017年1月1日至2022年8月31日期间通过影像学诊断为FLLs并接受EUS-FNA的88例患者的数据。将 EUS-FNA 活检结果与最终诊断结果进行比较，以评估诊断价值。分析相关因素对 EUS-FNA 活检结果的影响：结果：本研究分析的 88 例患者最终诊断为 86 例恶性肿瘤和 2 例良性肿瘤。EUS-FNA对FLL的总体诊断准确率为93.18%（82/88；95%置信区间[CI]，87.9-98.5），敏感性、特异性、阳性预测值和阴性预测值分别为93.02%（80/86；95%CI，87.6-98.4）、100%（2/2；95%CI，100-100）、100%（80/80；95%CI，100-100）和25%（2/8；95%CI，-5-55.0）。两组患者的病变和手术相关参数无明显差异（P> 0.05）。多穿刺和单穿刺组的穿刺针数差异有统计学意义（P = 0.001）：我们的数据显示，EUS-FNA 是一种安全可靠的 FLL 诊断方法，具有很高的准确性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinics and research in hepatology and gastroenterology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

4.30

自引率

3.70%

发文量

198

审稿时长

42 days

期刊介绍： Clinics and Research in Hepatology and Gastroenterology publishes high-quality original research papers in the field of hepatology and gastroenterology. The editors put the accent on rapid communication of new research and clinical developments and so called "hot topic" issues. Following a clear Editorial line, besides original articles and case reports, each issue features editorials, commentaries and reviews. The journal encourages research and discussion between all those involved in the specialty on an international level. All articles are peer reviewed by international experts, the articles in press are online and indexed in the international databases (Current Contents, Pubmed, Scopus, Science Direct). Clinics and Research in Hepatology and Gastroenterology is a subscription journal (with optional open access), which allows you to publish your research without any cost to you (unless you proactively chose the open access option). Your article will be available to all researchers around the globe whose institution has a subscription to the journal.