Incarceration Exposure, Biological Aging, and Depression Symptoms in an African American Sample of Older Adults.

IF 2.2 3区医学 Q2 GERONTOLOGY

Journal of Aging and Health Pub Date : 2024-05-31 DOI:10.1177/08982643241257065

Mark T Berg, Kendall Riley, Man-Kit Lei, Ronald L Simons

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Abstract

Objectives: The study draws upon perspectives on life-course stressors and health to assess whether lifetime incarceration exposure is a determinant of biological aging and self-reported depression. Methods: Using data from a sample of 460 African American participants (average age= 57) in the Family and Community Health Study, the study examined two epigenetic indices of biological aging, DunedinPoAm and GrimAge, as well as a self-reported measure of depression symptoms. Estimates were derived from multivariate regression models with adjustments for selection on observables and confounding factors. Results: Exposure to incarceration was a significant determinant of accelerated biological aging (GrimAge) and the pace of aging (DunedinPoAm) and depressive symptoms. Discussion: Among formerly incarcerated older adults, past experiences with the stressors of incarceration predict key biomarkers of physiological deterioration and depressive symptoms. Incarceration contributes to the mental and physical health burden of older adults.

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非裔美国老年人样本中的监禁暴露、生物衰老和抑郁症状。

研究目的：本研究从生命历程压力和健康的角度出发，评估终生监禁是否是生物衰老和自我报告抑郁的决定因素。研究方法该研究使用了家庭与社区健康研究中 460 名非洲裔美国人（平均年龄为 57 岁）参与者的样本数据，检查了生物衰老的两个表观遗传指数 DunedinPoAm 和 GrimAge，以及自我报告的抑郁症状测量值。估计值来自多变量回归模型，并对观察指标的选择和混杂因素进行了调整。结果显示监禁是加速生物衰老（GrimAge）、衰老速度（DunedinPoAm）和抑郁症状的重要决定因素。讨论：在曾被监禁的老年人中，过去的监禁压力经历可预测生理衰退和抑郁症状的关键生物标志物。监禁加重了老年人的身心健康负担。

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来源期刊

Journal of Aging and Health Multiple-

CiteScore

5.60

自引率

3.60%

发文量

113

期刊介绍： The Journal of Aging and Health is an interdisciplinary forum for the presentation of research findings and scholarly exchange in the area of aging and health. Manuscripts are sought that deal with social and behavioral factors related to health and aging. Disciplines represented include the behavioral and social sciences, public health, epidemiology, demography, health services research, nursing, social work, medicine, and related disciplines. Although preference is given to manuscripts presenting the findings of original research, review and methodological pieces will also be considered.