Computed Tomography Assessment of Severity of Acute Pancreatitis in Bangladeshi Children.

IF 1.3 Q3 PEDIATRICS

Pediatric Gastroenterology, Hepatology & Nutrition Pub Date : 2024-05-01 Epub Date: 2024-05-07 DOI:10.5223/pghn.2024.27.3.176

Kaniz Fathema, Bazlul Karim, Salahuddin Al-Azad, Md Rukunuzzaman, Mizu Ahmed, Tasfia Jannat Rifah, Dipanwita Saha, Md Benzamin

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引用次数: 0

Abstract

Purpose: Acute pancreatitis (AP) is common among children in Bangladesh. Its management depends mainly on risk stratification. This study aimed to assess the severity of pediatric AP using computed tomography (CT).

Methods: This cross-sectional, descriptive study was conducted in pediatric patients with AP at the Department of Pediatric Gastroenterology and Nutrition, BSMMU, Dhaka, Bangladesh.

Results: Altogether, 25 patients with AP were included, of whom 18 (mean age, 10.27±4.0 years) were diagnosed with mild AP, and 7 (mean age, 10.54±4.0 years) with severe AP. Abdominal pain was present in all the patients, and vomiting was present in 88% of the patients. Etiology was not determined. No significant differences in serum lipase, serum amylase, BUN, and CRP levels were observed between the mild and severe AP groups. Total and platelet counts as well as hemoglobin, hematocrit, serum creatinine, random blood sugar, and serum alanine aminotransferase levels (p>0.05) were significantly higher in the mild AP group than in the severe AP group (p=0.001). The sensitivity, specificity, positive predictive value, and negative predictive value of CT severity index (CTSI) were 71.4%, 72.2%, 50%, and 86.7%, respectively. In addition, significant differences in pancreatic appearance and necrosis were observed between the two groups on CT.

Conclusion: CT can be used to assess the severity of AP. In the present study, the CTSI effectively assessed the severity of AP in pediatric patients.

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孟加拉儿童急性胰腺炎严重程度的计算机断层扫描评估

目的：急性胰腺炎（AP）在孟加拉国儿童中很常见。其治疗主要取决于风险分层。本研究旨在使用计算机断层扫描（CT）评估小儿急性胰腺炎的严重程度：这项横断面描述性研究是在孟加拉国达卡 BSMMU 小儿胃肠病学和营养学系对患有 AP 的儿童患者进行的：共纳入 25 名 AP 患者，其中 18 人（平均年龄为 10.27±4.0 岁）被诊断为轻度 AP，7 人（平均年龄为 10.54±4.0 岁）被诊断为重度 AP。所有患者均出现腹痛，88%的患者出现呕吐。病因尚未确定。轻度和重度 AP 组的血清脂肪酶、血清淀粉酶、BUN 和 CRP 水平无明显差异。轻度 AP 组的总计数、血小板计数、血红蛋白、血细胞比容、血清肌酐、随机血糖和血清丙氨酸氨基转移酶水平（P>0.05）明显高于重度 AP 组（P=0.001）。CT 严重程度指数（CTSI）的敏感性、特异性、阳性预测值和阴性预测值分别为 71.4%、72.2%、50% 和 86.7%。此外，两组患者的胰腺外观和坏死情况在 CT 上有明显差异：结论：CT 可用于评估 AP 的严重程度。在本研究中，CTSI 能有效评估儿童患者 AP 的严重程度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Gastroenterology, Hepatology & Nutrition PEDIATRICS-

CiteScore

3.90

自引率

0.00%

发文量

期刊介绍： Pediatric Gastroenterology, Hepatology and Nutrition (Pediatr Gastroenterol Hepatol Nutr), an official journal of The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition, is issued bimonthly and published in English. The aim of Pediatr Gastroenterol Hepatol Nutr is to advance scientific knowledge and promote child healthcare by publishing high-quality empirical and theoretical studies and providing a recently updated knowledge to those practitioners and scholars in the field of pediatric gastroenterology, hepatology and nutrition. Pediatr Gastroenterol Hepatol Nutr publishes review articles, original articles, and case reports. All of the submitted papers are peer-reviewed. The journal covers basic and clinical researches on molecular and cellular biology, pathophysiology, epidemiology, diagnosis, and treatment of all aspects of pediatric gastrointestinal diseases and nutritional health problems.