Detecting novel psychoactive substances around the world.

IF 7.5 2区 医学 Q1 PSYCHIATRY
Current Opinion in Psychiatry Pub Date : 2024-07-01 Epub Date: 2024-04-22 DOI:10.1097/YCO.0000000000000939
Alberto Salomone, Marco Vincenti
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引用次数: 0

Abstract

Purpose of review: The worldwide spread of novel psychoactive substances (NPS) in the illicit drug market and their continuous increase in number and type, for the purpose of bypassing controlled substance legislation, represents a continuing challenge for forensic scientists, clinicians and enforcement authorities. We aim to provide information regarding the most urgent harms related to NPS consumption in different world regions and the current state of the art for NPS analysis.

Recent findings: Unfortunately, the identification of NPS in biological samples is controversial, especially when samples are limited, or the drug is promptly and extensively metabolized. This causes a lack of information on their real diffusion in different parts of the world and in different populations. New technologies and instrumental detection of NPS in alternative samples are offering comprehensive information about NPS use.

Summary: The lack of detection and underreporting of NPS in biological samples makes it difficult to obtain complete qualitative and quantitative information about NPS prevalence. The most innovative strategies that have been proposed in the last 2 years to assist NPS analysis and possibly facilitate the understanding of the NPS diffusion around the world are presented.

在全球范围内检测新型精神活性物质。
审查目的:新型精神活性物质(NPS)在非法药物市场上的全球蔓延及其数量和种类的不断增加,目的是绕过受管制物质的立法,这对法医科学家、临床医生和执法当局来说是一个持续的挑战。我们旨在提供有关世界不同地区与 NPS 消费相关的最紧迫危害以及 NPS 分析技术现状的信息:遗憾的是,生物样本中 NPS 的鉴定存在争议,特别是当样本有限或药物被迅速和广泛代谢时。这导致缺乏有关其在世界不同地区和不同人群中实际传播情况的信息。在替代样本中检测 NPS 的新技术和仪器正在提供有关 NPS 使用情况的全面信息。摘要:由于在生物样本中缺乏对 NPS 的检测和报告不足,因此难以获得有关 NPS 流行情况的完整定性和定量信息。本文介绍了过去两年中提出的最具创新性的战略,这些战略有助于对 NPS 进行分析,并有可能促进对 NPS 在全球扩散情况的了解。
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来源期刊
Current Opinion in Psychiatry
Current Opinion in Psychiatry 医学-精神病学
CiteScore
12.20
自引率
1.40%
发文量
76
审稿时长
6-12 weeks
期刊介绍: Current Opinion in Psychiatry is an easy-to-digest bimonthly journal covering the most interesting and important advances in the field of psychiatry. Eight sections on mental health disorders including schizophrenia, neurodevelopmental disorders and eating disorders, are presented alongside five area-specific sections, offering an expert evaluation on the most exciting developments in the field.
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