Building up complexity in structural biology studies

IF 12.5 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
Eva Nogales
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引用次数: 0

Abstract

Macromolecules are involved in myriads of interactions that regulate their cellular function. While years of structural biology progress was built by reducing this complexity, a molecular understanding of biological processes requires the characterization of ever larger and more dynamic molecular assemblies. Cryo-electron microscopy is rising to this challenge.
提高结构生物学研究的复杂性
大分子参与了无数调节细胞功能的相互作用。虽然多年来结构生物学的进步是通过降低这种复杂性取得的,但要从分子角度了解生物过程,就必须对更大和更动态的分子组装进行表征。冷冻电镜技术正在迎接这一挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Nature Structural & Molecular Biology
Nature Structural & Molecular Biology BIOCHEMISTRY & MOLECULAR BIOLOGY-BIOPHYSICS
CiteScore
22.00
自引率
1.80%
发文量
160
审稿时长
3-8 weeks
期刊介绍: Nature Structural & Molecular Biology is a comprehensive platform that combines structural and molecular research. Our journal focuses on exploring the functional and mechanistic aspects of biological processes, emphasizing how molecular components collaborate to achieve a particular function. While structural data can shed light on these insights, our publication does not require them as a prerequisite.
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