A pair epimers of eremophilane sesquiterpene from Ligularia macrophylla

IF 1 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY

Journal of Chemical Research Pub Date : 2024-05-27 DOI:10.1177/17475198241255788

Tong Shen, Xiang-Tao Zha, Mei Yu, Guo-Li Li, Yi-Lin He

引用次数: 0

Abstract

Two oxygenated eremophilane-type sesquiterpenoids, possessing C21 skeleton, a pair epimers, have been isolated from the whole plants of Ligularia macrophylla (Compositae). Their structures were determined by analysis of infrared, ultraviolet, nuclear magnetic resonance, high-resolution electrospray ionization mass spectrometry data, and electronic circular dichroism as well as comparison with literature data. Of the two compounds, the compound 1 is unknown, and the other is known. These compounds are evaluated for antibacterial activity of Staphylococcus aureus, Escherichia coli, Bacillus subtilis, and Bacillus cereus.

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大叶女贞中的一对epimers of eremophilane sesquiterpene

从大戟科植物大戟（Ligularia macrophylla）的全株中分离出了两种含氧的勃氏倍半萜类化合物，它们具有 C21 骨架和一对表聚体。通过分析红外光谱、紫外光谱、核磁共振、高分辨率电喷雾电离质谱数据、电子圆二色性以及与文献数据的比较，确定了它们的结构。在这两种化合物中，化合物 1 是未知的，另一种是已知的。评估了这些化合物对金黄色葡萄球菌、大肠杆菌、枯草杆菌和蜡样芽孢杆菌的抗菌活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Chemical Research CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

2.30

自引率

0.00%

发文量

审稿时长

1.0 months

期刊介绍： The Journal of Chemical Research is a monthly journal which has a broad international authorship and publishes research papers and reviews in all branches of experimental chemistry. Established in 1977 as a joint venture by the British, French and German chemical societies it maintains the high standards set by the founding societies. Each paper is independently peer reviewed and only carefully evaluated contributions are accepted. Recent papers have described new synthetic methods, new heterocyclic compounds, new natural products, and the inorganic chemistry of metal complexes.