Abducens Nerve Palsy in a Patient with COVID-19: A Case Report.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL

Medical Bulletin of Sisli Etfal Hospital Pub Date : 2024-04-05 eCollection Date: 2024-01-01 DOI:10.14744/SEMB.2023.55491

Gulten Tata, Sahin Isik, Husrev Diktas, Gencer Genc, Serpil Bulut

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Abstract

Numerous neurological manifestations associated with COVID-19 have been reported. However, abducens nerve palsy (ANP) associated with COVID-19 is very rare and mostly related to accompanying respiratory symptoms. Here we present a 29-year-old woman with unilateral ANP manifesting with diplopia and positive SARS-CoV-2 S antibodies, which were checked later. On admission, she had signs of viral pneumonia in thorax CT without any respiratory symptoms. Her cranial neuroimaging revealed no abnormality. Following treatment with favipiravir 2x1600 mg loading dose and then 2x600mg daily maintenance, dexamethasone 8 mg/day and enoxaparin 6000 IU/day, her CT findings recovered completely whereas her ANP only partially resolved. One week after the end of COVID-19 treatment, she also developed Herpes simplex keratitis which was successfully treated with valacyclovir. It should be kept in mind that isolated abducens nerve palsy may be the only finding of COVID-19 cases without any respiratory symptoms.

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一名 COVID-19 患者的视神经麻痹：病例报告

有许多与 COVID-19 相关的神经系统表现的报道。然而，与 COVID-19 相关的外展神经麻痹（ANP）却非常罕见，而且大多与伴随的呼吸道症状有关。在此，我们介绍了一名 29 岁女性患者，她患有单侧视神经麻痹，表现为复视和 SARS-CoV-2 S 抗体阳性，后经检查为 SARS-CoV-2 S 抗体阳性。入院时，她的胸部 CT 显示有病毒性肺炎的迹象，但没有任何呼吸道症状。头颅神经影像学检查未发现异常。在使用法非拉韦 2x1600 毫克负荷剂量、然后每天 2x600 毫克维持剂量、地塞米松 8 毫克/天和依诺肝素 6000 IU/天的治疗后，她的 CT 结果完全恢复，而 ANP 仅部分缓解。COVID-19 治疗结束一周后，她又患上了单纯疱疹性角膜炎，经伐昔洛韦治疗后获得成功。需要注意的是，孤立的外展神经麻痹可能是没有任何呼吸道症状的 COVID-19 病例的唯一发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Medical Bulletin of Sisli Etfal Hospital MEDICINE, GENERAL & INTERNAL-

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16.70%

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