Weathered polyethylene microplastics induced immunomodulation in zebrafish

IF 5.4 3区材料科学 Q2 CHEMISTRY, PHYSICAL

ACS Applied Energy Materials Pub Date : 2024-05-25 DOI:10.1016/j.etap.2024.104478

Thilagam Harikrishnan , Pandi Paramasivam , Anusuya Sankar , Madhavan Sakthivel , Elumalai Sanniyasi , Thiagarajan Raman , Muthukumar Thangavelu , Gopalakrishnan Singaram , Govarthanan Muthusamy

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引用次数: 0

Abstract

Microplastics are pollutants of emerging concern and the aquatic biota consumes microplastics (MPs), which has a range of toxicological and environmental effects on aquatic organisms that are not the intended targets. The current study looked into how weathered polyethylene (wPE) MPs affected Danio albolineatus immunological and haematological markers. In this experiment, fish of both sexes were placed in control and exposure groups, and they were exposed for 40 d at the sublethal level (1 μg L^-1) of fragmented wPE, which contained 1074 ± 52 MPs per litre. Similarly, fish exposed to wPE MPs showed significant modifications in lysozyme, antimicrobial, and antiprotease activity, as well as differential counts. Results of the present study show that the male fish were more susceptible than female fish after 40 d of chronic exposure. Further studies are needed to ascertain how the innate and humoral immune systems of the fish respond to MPs exposure.

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风化聚乙烯微塑料诱导斑马鱼的免疫调节。

微塑料是新出现的令人担忧的污染物，水生生物群消耗微塑料（MPs），会对非预期目标的水生生物产生一系列毒理学和环境影响。目前的研究探讨了风化聚乙烯（wPE）MPs 如何影响白腹丹顶鹤的免疫学和血液学指标。在该实验中，雌雄鱼类被分为对照组和暴露组，它们在亚致死水平（1μgL-1）的破碎聚乙烯中暴露 40 天，每升聚乙烯中含有 1074 ± 52 种 MPs。同样，暴露于 wPE MPs 的鱼类在溶菌酶、抗菌和抗蛋白酶活性以及差异计数方面都出现了显著变化。本研究结果表明，长期接触 40 天后，雄鱼比雌鱼更易受影响。要确定鱼类的先天性免疫系统和体液免疫系统如何应对 MPs 暴露，还需要进一步的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Energy Materials Materials Science-Materials Chemistry

CiteScore

10.30

自引率

6.20%

发文量

1368

期刊介绍： ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.