Twenty shades of the mosaic of autoimmunity

IF 9.2 1区 医学 Q1 IMMUNOLOGY
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引用次数: 0

Abstract

Accelerated, inflammatory atherosclerosis and cardiovascular disease have been associated with several autoimmune diseases including RA, AS, SLE, APS and SSc. Non-invasive, ultrasound- based techniques are suitable for the assessment of preclinical vascular pathophysiology. Multiple vascular and other biomarkers including vitamin D, ferritin, prolactin, suPAR, BNP fragments, oxLDL/β2GPI complexes, anti-Hsp60 and others have been associated with cardiometabolic comorbidities. The control of the underlying inflammatory disease is crucial for minimising cardiovascular risk in autoimmune diseases.

自体免疫马赛克的二十种色调。
炎症性动脉粥样硬化和心血管疾病的加速与多种自身免疫性疾病有关,包括 RA、AS、SLE、APS 和 SSc。基于超声波的无创技术适用于临床前血管病理生理学评估。包括维生素 D、铁蛋白、催乳素、suPAR、BNP 片段、oxLDL/β2GPI 复合物、抗 Hsp60 等在内的多种血管和其他生物标记物与心脏代谢合并症有关。控制潜在的炎症性疾病对于降低自身免疫性疾病的心血管风险至关重要。
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来源期刊
Autoimmunity reviews
Autoimmunity reviews 医学-免疫学
CiteScore
24.70
自引率
4.40%
发文量
164
审稿时长
21 days
期刊介绍: Autoimmunity Reviews is a publication that features up-to-date, structured reviews on various topics in the field of autoimmunity. These reviews are written by renowned experts and include demonstrative illustrations and tables. Each article will have a clear "take-home" message for readers. The selection of articles is primarily done by the Editors-in-Chief, based on recommendations from the international Editorial Board. The topics covered in the articles span all areas of autoimmunology, aiming to bridge the gap between basic and clinical sciences. In terms of content, the contributions in basic sciences delve into the pathophysiology and mechanisms of autoimmune disorders, as well as genomics and proteomics. On the other hand, clinical contributions focus on diseases related to autoimmunity, novel therapies, and clinical associations. Autoimmunity Reviews is internationally recognized, and its articles are indexed and abstracted in prestigious databases such as PubMed/Medline, Science Citation Index Expanded, Biosciences Information Services, and Chemical Abstracts.
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