Aditi Vashisht, Arvind Krishna, Robin Chugh, Abhinav David, Divyanshu Srivastava
{"title":"PRP and its benefit as an adjunctive therapy with subcision and microneedling in atrophic scars: a comparative study.","authors":"Aditi Vashisht, Arvind Krishna, Robin Chugh, Abhinav David, Divyanshu Srivastava","doi":"10.4103/JCAS.JCAS_64_23","DOIUrl":null,"url":null,"abstract":"<p><strong>Context: </strong>Scarring is a biological process of wound repair which leads to a difference in the normal structure and function of the skin and manifests as a depressed or raised area. Treatment of scars is challenging. A number of therapeutic approaches like surgical techniques and non-surgical techniques are performed to improve scarring.</p><p><strong>Aims and objectives: </strong>The aim of this study was to compare the outcome of subcision followed by microneedling versus subcision followed by microneedling and topical platelet-rich plasma (PRP) in atrophic scars.</p><p><strong>Materials and methods: </strong>A comparative prospective study was conducted at a tertiary care hospital in North India to compare the efficacy of subcision followed by microneedling versus subcision followed by microneedling and topical PRP. A total of 40 cases were taken and were randomly divided into two groups, A and B of 20 patients in each group. Topical PRP was applied as an additional therapy in Group B in the same sitting. Minimum three sittings were done in each patient at an interval of 4 weeks and results were assessed after 1 month of the third session. The statistical software used is Microsoft Excel and SPSS software program, version 24.0 for analysis of data and Microsoft Word to generate graphs and tables.</p><p><strong>Results: </strong>Improvement in scar grading was more in Group B as compared to Group A with statistically significant difference (<i>P =</i> 0.032). There was an improvement in scar grading from grade 4 scar to grade 2 in 15% and 30% patients of Groups A and B, respectively, with improvement in skin texture and pigmentation more in Group B.</p><p><strong>Conclusion: </strong>PRP proved to add to the improvement of grade of atrophic scars when combined with subcision and microneedling.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 2","pages":"137-145"},"PeriodicalIF":0.0000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126227/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cutaneous and Aesthetic Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/JCAS.JCAS_64_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Context: Scarring is a biological process of wound repair which leads to a difference in the normal structure and function of the skin and manifests as a depressed or raised area. Treatment of scars is challenging. A number of therapeutic approaches like surgical techniques and non-surgical techniques are performed to improve scarring.
Aims and objectives: The aim of this study was to compare the outcome of subcision followed by microneedling versus subcision followed by microneedling and topical platelet-rich plasma (PRP) in atrophic scars.
Materials and methods: A comparative prospective study was conducted at a tertiary care hospital in North India to compare the efficacy of subcision followed by microneedling versus subcision followed by microneedling and topical PRP. A total of 40 cases were taken and were randomly divided into two groups, A and B of 20 patients in each group. Topical PRP was applied as an additional therapy in Group B in the same sitting. Minimum three sittings were done in each patient at an interval of 4 weeks and results were assessed after 1 month of the third session. The statistical software used is Microsoft Excel and SPSS software program, version 24.0 for analysis of data and Microsoft Word to generate graphs and tables.
Results: Improvement in scar grading was more in Group B as compared to Group A with statistically significant difference (P = 0.032). There was an improvement in scar grading from grade 4 scar to grade 2 in 15% and 30% patients of Groups A and B, respectively, with improvement in skin texture and pigmentation more in Group B.
Conclusion: PRP proved to add to the improvement of grade of atrophic scars when combined with subcision and microneedling.
期刊介绍：
The journal will cover aspects of Dermatosurgery and Aesthetic surgery, including cutaneous surgical procedures, lasers, light based treatments and aesthetic treatments. Authors of articles addressing topics such as skin tumours, pigmentary disorders, histopathology, diagnostic techniques, drugs, applications of cosmeceuticals surgical aspects, including pre and post procedural care are highly encouraged to submit with us. The journal also publishes articles on topics in allied specialities suh as plastic surgery, maxillofacial surgery vascular surgery, oculoplastic surgery etc. that are relevant to Dermatosurgery. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed Original Research Articles, Systematic reviews, Narrative Reviews, Case reports, Innovations and Debates. Letters to the editor, practice points, pearls in cutaneous and aesthetic surgery, quiz page, images, novel techniques, newer uses of instruments and video presentations and ethical aspects of cutaneous and aesthetic surgery are also invited.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
