Evaluation Study of Petroselinum Crispum Extract Toward Pathogenic Isolates of candida

Afrah Talib Abdullah, Adnan B. Al-Hawash
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Abstract

Objectives: The aim of this study was to isolation and identify the isolated genetically if candida species from candidiasis infection and study the activity of bioactive compounds. Methods: Samples were obtained from 28 patients from the mouth of patients with oral candidiasis. Samples were collected from the Child Specialized Hospital, Al-Faiha General Hospital Dermatologist Dr. Laith Globe Lazim Al-Kinani (Master of Dermatology, PhD in Dermatology, Iraqi Ministry of Health, Al-Fayhaa Teaching Hospital) aided in the diagnosis of clinical cases and molecular analysis then tested the activity of the mint plant extract on it and compared it with the antifungal nystatin. Results: Mint leaf extract showed activity against Candida isolates. The extract was non-toxic, and C. albicans was the most common Candida. Conclusions: The methanolic extract of Petroselinum crispum in this study showed good inhibition activity against the isolated Candida species.
针对念珠菌致病性菌株的 Petroselinum Crispum 提取物评估研究
研究目的本研究旨在分离和鉴定从念珠菌感染中分离出的遗传性念珠菌物种,并研究生物活性化合物的活性。研究方法从 28 名口腔念珠菌病患者的口腔中采集样本。样本采集自儿童专科医院、Al-Faiha 综合医院皮肤科医生 Laith Globe Lazim Al-Kinani 博士(伊拉克卫生部 Al-Fayhaa 教学医院皮肤科硕士、皮肤科博士),他协助诊断了临床病例并进行了分子分析,然后测试了薄荷植物提取物的活性,并与抗真菌药物奈司他丁进行了比较。结果薄荷叶提取物对白色念珠菌分离株具有活性。提取物无毒,白念珠菌是最常见的念珠菌。结论本研究中的薄荷叶甲醇提取物对分离出的念珠菌具有良好的抑制活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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