Umer Bakali , Chitvan Killawala , Evelise Monteagudo , Emre Dikici , Sapna K. Deo , Sylvia Daunert
{"title":"Exhaled breath analysis applications for evaluating occupational and environmental exposures","authors":"Umer Bakali , Chitvan Killawala , Evelise Monteagudo , Emre Dikici , Sapna K. Deo , Sylvia Daunert","doi":"10.1016/j.trac.2024.117787","DOIUrl":null,"url":null,"abstract":"<div><p>Although exhaled breath analysis for diagnosing human health is a concept that dates to antiquity, the application of modern analytical and collection techniques to exhaled breath analysis has rapidly evolved the field. Distinct phases of breath, including breath gas, condensate, and aerosols have been defined in the literature. Although traditionally used for clinical diagnostics, breath analysis has significant applications in evaluating occupational and environmental exposures. Breath analysis can reveal exposure compounds and their metabolites as well as biomarkers of oxidative stress and inflammation. As this field grows, new developments in exposure monitoring have implications for informing policy, best practices, and remediation to help reduce occupational and environmental exposures. This review aims to guide prospective research in breath analysis for exposure monitoring by summarizing current techniques and analytes of interest in a variety of occupational and environmental contexts, while highlighting knowledge gaps to be addressed.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8000,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S016599362400270X","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Although exhaled breath analysis for diagnosing human health is a concept that dates to antiquity, the application of modern analytical and collection techniques to exhaled breath analysis has rapidly evolved the field. Distinct phases of breath, including breath gas, condensate, and aerosols have been defined in the literature. Although traditionally used for clinical diagnostics, breath analysis has significant applications in evaluating occupational and environmental exposures. Breath analysis can reveal exposure compounds and their metabolites as well as biomarkers of oxidative stress and inflammation. As this field grows, new developments in exposure monitoring have implications for informing policy, best practices, and remediation to help reduce occupational and environmental exposures. This review aims to guide prospective research in breath analysis for exposure monitoring by summarizing current techniques and analytes of interest in a variety of occupational and environmental contexts, while highlighting knowledge gaps to be addressed.
期刊介绍:
TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.