Managing sexual health challenges in breast cancer survivors: A comprehensive review

IF 5.7 2区医学 Q1 OBSTETRICS & GYNECOLOGY

Breast Pub Date : 2024-05-24 DOI:10.1016/j.breast.2024.103754

Linda Cucciniello , Federica Miglietta , Valentina Guarneri , Fabio Puglisi

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引用次数: 0

Abstract

The significant advancements in breast cancer management have led to an increase in the prevalence of breast cancer survivors. Despite their efficacy, these treatments can cause a variable range of side effects, significantly deteriorating the patients’ quality of life.

Sexual dysfunction, and in particular the genitourinary syndrome of menopause, represent one of the major causes of quality-of-life impairment among breast cancer patients, potentially affecting treatment adherence and compliance. If in the general population, hypoestrogenism-related symptoms are typically managed through systemic or topical estrogen administration, this approach is contraindicated in breast cancer patients for the potential increased risk of disease recurrence, urging the investigation of alternative measures.

The aim of this review is to summarize the most up-to-date pharmacological and non-pharmacological interventions, as well as supportive measures, available for the management of sexual dysfunctions in breast cancer patients and survivors.

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应对乳腺癌幸存者的性健康挑战：全面回顾

乳腺癌治疗方面的重大进展导致乳腺癌幸存者人数增加。性功能障碍，尤其是更年期泌尿生殖系统综合征，是乳腺癌患者生活质量受损的主要原因之一，可能会影响治疗的依从性和顺应性。如果说在普通人群中，与雌激素过低相关的症状通常是通过全身或局部服用雌激素来控制的，那么在乳腺癌患者中，这种方法是禁忌的，因为可能会增加疾病复发的风险，因此需要研究替代措施。本综述旨在总结最新的药物和非药物干预措施以及支持性措施，用于控制乳腺癌患者和幸存者的性功能障碍。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Breast 医学-妇产科学

CiteScore

8.70

自引率

2.60%

发文量

165

审稿时长

59 days

期刊介绍： The Breast is an international, multidisciplinary journal for researchers and clinicians, which focuses on translational and clinical research for the advancement of breast cancer prevention, diagnosis and treatment of all stages.