Neonatal Tetanus at the Dawn of 2023: A Case Report

R. Dahni, F. Z. Khayi, S. El Moussaoui, W. Lahmini, M. Bourrous
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Abstract

Neonatal tetanus is a toxi-infection caused by Clostridium tetani, with a neurological tropism, causing significant morbidity and mortality in newborns in developing countries. The infection almost always starts in the umbilical cord. Diagnosis is clinical. Treatment is two-pronged: etiological (specific immunoglobulins, antibiotic therapy, anti-tetanus vaccination and treatment of the portal of entry) and symptomatic (sedatives and muscle relaxants, curarization). Prevention is the only effective option, and relies on vaccination of mothers during pregnancy and health education of the population. We report the case of a newborn hospitalized for neonatal tetanus and treated with antibiotic therapy combined with intrathecal serotherapy, with a good evolution.
2023 年伊始的新生儿破伤风:病例报告
新生儿破伤风是一种由破伤风梭菌引起的毒素感染,具有神经系统毒性,在发展中国家造成新生儿大量发病和死亡。感染几乎总是从脐带开始。临床诊断。治疗是双管齐下的:病因治疗(特异性免疫球蛋白、抗生素治疗、抗破伤风疫苗接种和入口治疗)和对症治疗(镇静剂和肌肉松弛剂、治疗)。预防是唯一有效的办法,这有赖于母亲在怀孕期间接种疫苗和对民众进行健康教育。我们报告了一例因新生儿破伤风住院治疗的新生儿病例,该新生儿在接受抗生素治疗的同时,还接受了鞘内血清疗法,病情发展良好。
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